Description

Description

4-Bromo-2,5-difluorobenzenesulfonyl Chloride (CAS No. 13656-57-0) is a high-purity, reactive sulfonyl chloride derivative widely used in organic synthesis and pharmaceutical research. This compound, with the molecular formula C₆H₂BrClF₂O₂S, is characterized by its bromo and difluoro substituents on the benzene ring, which enhance its reactivity in nucleophilic substitution and coupling reactions. Its IUPAC name is 4-bromo-2,5-difluorobenzenesulfonyl chloride, and it is available in various packaging options to suit laboratory-scale and industrial applications. Ideal for researchers developing sulfonamide-based compounds, this reagent is rigorously tested for purity and stability, ensuring consistent performance in synthetic workflows. Store in a cool, dry place under inert conditions to maintain its integrity.

Application

4-Bromo-2,5-difluorobenzenesulfonyl Chloride is a versatile building block in medicinal chemistry, particularly for the synthesis of sulfonamide derivatives with potential biological activity. It is employed in the preparation of enzyme inhibitors, receptor antagonists, and other pharmacologically active molecules. The compound’s reactivity makes it valuable for introducing sulfonyl groups into aromatic systems under mild conditions. Researchers also utilize it in cross-coupling reactions to create complex heterocyclic scaffolds for drug discovery. Its stability and selectivity render it suitable for high-throughput screening and combinatorial chemistry applications.

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