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Atomfair 4-Bromo-2-(trifluoromethyl)benzonitrile C8H3BrF3N

Description 4-Bromo-2-(trifluoromethyl)benzonitrile (CAS No. 191165-13-6) is a high-purity halogenated aromatic compound with the molecular formula C8H3BrF3N. This specialized chemical features a bromo substituent at the 4-position and a trifluoromethyl group at the 2-position of a benzonitrile scaffold, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. With a molecular weight of 250.02 g/mol, it is supplied as a crystalline solid with ??95% purity (HPLC) and is rigorously tested for consistency. Ideal for cross-coupling reactions, nucleophilic substitutions, and fluorinated building block applications. Packaged under inert gas in amber glass vials to ensure stability.

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Description

Description

4-Bromo-2-(trifluoromethyl)benzonitrile (CAS No. 191165-13-6) is a high-purity halogenated aromatic compound with the molecular formula C8H3BrF3N. This specialized chemical features a bromo substituent at the 4-position and a trifluoromethyl group at the 2-position of a benzonitrile scaffold, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. With a molecular weight of 250.02 g/mol, it is supplied as a crystalline solid with ??95% purity (HPLC) and is rigorously tested for consistency. Ideal for cross-coupling reactions, nucleophilic substitutions, and fluorinated building block applications. Packaged under inert gas in amber glass vials to ensure stability.

  • CAS No: 191165-13-6
  • Molecular Formula: C8H3BrF3N
  • Molecular Weight: 250.01
  • Exact Mass: 248.94010
  • Monoisotopic Mass: 248.94010
  • IUPAC Name: 4-bromo-2-(trifluoromethyl)benzonitrile
  • SMILES: C1=CC(=C(C=C1Br)C(F)(F)F)C#N
  • Synonyms: 4-Bromo-2-(trifluoromethyl)benzonitrile, 191165-13-6, DTXSID90624956, DTXCID60575709, 642-806-0

Application

4-Bromo-2-(trifluoromethyl)benzonitrile serves as a key precursor in Suzuki-Miyaura and Buchwald-Hartwig couplings for drug discovery. Its trifluoromethyl group enhances metabolic stability in bioactive molecules, while the bromo and nitrile functionalities allow further derivatization. Commonly used in the synthesis of herbicides, kinase inhibitors, and PET radioligands. Suitable for heterocycle formation via cyclization reactions.

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