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Atomfair 4-Bromo-2-fluoropyridine C5H3BrFN

Description 4-Bromo-2-fluoropyridine (CAS No. 128071-98-7) is a high-purity halogenated pyridine derivative with the molecular formula C5H3BrFN . This heterocyclic compound features a bromine substituent at the 4-position and a fluorine atom at the 2-position of the pyridine ring, offering versatile reactivity for cross-coupling reactions , nucleophilic substitutions , and pharmaceutical intermediate synthesis . Ideal for researchers in medicinal chemistry and material science, this compound is supplied as a clear to pale-yellow liquid (or low-melting solid) with ??95% purity (GC). Store under inert atmosphere at 2-8??C to prevent degradation. Compatible with Suzuki-Miyaura , Buchwald-Hartwig , and SNAr reactions .

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Description

Description

4-Bromo-2-fluoropyridine (CAS No. 128071-98-7) is a high-purity halogenated pyridine derivative with the molecular formula C5H3BrFN. This heterocyclic compound features a bromine substituent at the 4-position and a fluorine atom at the 2-position of the pyridine ring, offering versatile reactivity for cross-coupling reactions, nucleophilic substitutions, and pharmaceutical intermediate synthesis. Ideal for researchers in medicinal chemistry and material science, this compound is supplied as a clear to pale-yellow liquid (or low-melting solid) with ??95% purity (GC). Store under inert atmosphere at 2-8??C to prevent degradation. Compatible with Suzuki-Miyaura, Buchwald-Hartwig, and SNAr reactions.

  • CAS No: 128071-98-7
  • Molecular Formula: C5H3BrFN
  • Molecular Weight: 175.99
  • Exact Mass: 174.94329
  • Monoisotopic Mass: 174.94329
  • IUPAC Name: 4-bromo-2-fluoropyridine
  • SMILES: C1=CN=C(C=C1Br)F
  • Synonyms: 4-Bromo-2-fluoropyridine, 128071-98-7, DTXSID00376510, DTXCID10327538, 672-942-6

Application

4-Bromo-2-fluoropyridine serves as a key building block in the synthesis of agrochemicals, pharmaceuticals, and ligands for catalysis. Its electron-deficient pyridine ring facilitates regioselective functionalization, making it valuable for kinase inhibitor development and PET tracer precursors. The compound is also used in metal-organic framework (MOF) design and functional material research.

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