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Atomfair 3,5-Difluorobenzenesulfonyl chloride C6H3ClF2O2S

Description 3,5-Difluorobenzenesulfonyl chloride (CAS No. 210532-25-5) is a high-purity sulfonyl chloride derivative with the molecular formula C6H3ClF2O2S . This compound is a versatile reagent widely used in organic synthesis, particularly in the preparation of sulfonamides and sulfonate esters. Its unique 3,5-difluoro substitution pattern enhances reactivity and selectivity in electrophilic aromatic substitution reactions. Ideal for pharmaceutical and agrochemical research, this compound is supplied as a crystalline solid with >98% purity (HPLC), ensuring consistent performance in demanding synthetic applications. Proper handling under inert conditions is recommended due to its moisture sensitivity.

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Description

Description

3,5-Difluorobenzenesulfonyl chloride (CAS No. 210532-25-5) is a high-purity sulfonyl chloride derivative with the molecular formula C6H3ClF2O2S. This compound is a versatile reagent widely used in organic synthesis, particularly in the preparation of sulfonamides and sulfonate esters. Its unique 3,5-difluoro substitution pattern enhances reactivity and selectivity in electrophilic aromatic substitution reactions. Ideal for pharmaceutical and agrochemical research, this compound is supplied as a crystalline solid with >98% purity (HPLC), ensuring consistent performance in demanding synthetic applications. Proper handling under inert conditions is recommended due to its moisture sensitivity.

  • CAS No: 210532-25-5
  • Molecular Formula: C6H3ClF2O2S
  • Molecular Weight: 212.60
  • Exact Mass: 211.9510345
  • Monoisotopic Mass: 211.9510345
  • IUPAC Name: 3,5-difluorobenzenesulfonyl chloride
  • SMILES: C1=C(C=C(C=C1F)S(=O)(=O)Cl)F
  • Synonyms: 3,5-Difluorobenzenesulfonyl chloride, 210532-25-5, DTXSID30378865, DTXCID30329892, 625-780-5

Application

3,5-Difluorobenzenesulfonyl chloride is primarily employed as a key intermediate in the synthesis of biologically active sulfonamide compounds. It is widely used in pharmaceutical research for developing enzyme inhibitors and receptor modulators. Additionally, this reagent finds applications in material science for modifying polymer surfaces and creating specialized coatings. Its reactivity with amines and alcohols makes it valuable for constructing complex molecular architectures in medicinal chemistry.

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