Description

Description

3-Bromo-6-methoxy-2-methylpyridine (CAS No. 126717-59-7) is a high-purity, organobromine compound with the molecular formula C₇H₈BrNO. This heterocyclic aromatic compound features a pyridine core substituted with bromine at the 3-position, a methoxy group at the 6-position, and a methyl group at the 2-position, offering versatile reactivity for synthetic applications. Ideal for pharmaceutical intermediates, agrochemical research, and ligand synthesis, this compound is rigorously tested via GC/MS, HPLC, and NMR to ensure ??95% purity. Packaged under inert gas in amber glass vials to ensure stability, it is suitable for use in cross-coupling reactions, functional group transformations, and as a building block in medicinal chemistry. Store in a cool, dry place away from light and moisture.

Application

3-Bromo-6-methoxy-2-methylpyridine serves as a key intermediate in the synthesis of bioactive molecules, particularly in pharmaceutical and agrochemical research. Its bromine moiety enables participation in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex heterocycles. The methoxy and methyl groups enhance electron density, making it useful for designing ligands in catalysis or modulators in drug discovery. Researchers also employ it in the development of kinase inhibitors and other small-molecule therapeutics.

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