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Atomfair 3-Bromo-5-(trifluoromethyl)pyridine C6H3BrF3N

Description 3-Bromo-5-(trifluoromethyl)pyridine (CAS No. 436799-33-6) is a high-purity halogenated pyridine derivative with the molecular formula C6H3BrF3N . This compound features a bromine substituent at the 3-position and a trifluoromethyl group at the 5-position of the pyridine ring, offering unique reactivity for nucleophilic substitution and cross-coupling reactions. Ideal for pharmaceutical, agrochemical, and materials science research, it is supplied as a clear to pale-yellow liquid or low-melting solid with ??98% purity (GC). Store under inert conditions at 2-8??C to prevent degradation. Available in amber glass vials (100mg to 25g) with optional COA and NMR spectra.

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Description

Description

3-Bromo-5-(trifluoromethyl)pyridine (CAS No. 436799-33-6) is a high-purity halogenated pyridine derivative with the molecular formula C6H3BrF3N. This compound features a bromine substituent at the 3-position and a trifluoromethyl group at the 5-position of the pyridine ring, offering unique reactivity for nucleophilic substitution and cross-coupling reactions. Ideal for pharmaceutical, agrochemical, and materials science research, it is supplied as a clear to pale-yellow liquid or low-melting solid with ??98% purity (GC). Store under inert conditions at 2-8??C to prevent degradation. Available in amber glass vials (100mg to 25g) with optional COA and NMR spectra.

  • CAS No: 436799-33-6
  • Molecular Formula: C6H3BrF3N
  • Molecular Weight: 225.99
  • Exact Mass: 224.94010
  • Monoisotopic Mass: 224.94010
  • IUPAC Name: 3-bromo-5-(trifluoromethyl)pyridine
  • SMILES: C1=C(C=NC=C1Br)C(F)(F)F
  • Synonyms: 3-Bromo-5-(trifluoromethyl)pyridine, 436799-33-6, DTXSID50456230, DTXCID90407049, 626-819-9

Application

3-Bromo-5-(trifluoromethyl)pyridine serves as a versatile building block in Suzuki-Miyaura and Buchwald-Hartwig couplings for drug discovery, particularly in kinase inhibitor development. The trifluoromethyl group enhances metabolic stability in agrochemical candidates, while the bromine enables palladium-catalyzed functionalization for material science applications. Researchers value its utility in creating fluorinated liquid crystals and electronic materials.

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