Description

Description

3-Bromo-5-methylpyridine-2-carboxylic acid (CAS No. 1211515-68-2) is a high-purity heterocyclic carboxylic acid derivative with the molecular formula C₇H₆BrNO₂. This compound features a pyridine core substituted with a bromine atom at the 3-position, a methyl group at the 5-position, and a carboxylic acid moiety at the 2-position, making it a versatile building block for pharmaceutical and agrochemical synthesis. With a molecular weight of 216.03 g/mol, it is supplied as a fine white to off-white crystalline powder, ensuring optimal solubility in polar organic solvents. Ideal for researchers and industrial chemists, this product is rigorously tested via HPLC, NMR, and mass spectrometry to guarantee ??98% purity. Suitable for use in cross-coupling reactions, metal-catalyzed transformations, and as a precursor for bioactive molecule development.

Application

3-Bromo-5-methylpyridine-2-carboxylic acid serves as a key intermediate in the synthesis of pharmaceuticals, particularly for the development of kinase inhibitors and antiviral agents. Its reactive bromine and carboxylic acid groups enable facile derivatization for drug discovery pipelines. This compound is also employed in material science for constructing functionalized pyridine-based ligands in catalysis. Researchers utilize it in Suzuki-Miyaura and Buchwald-Hartwig coupling reactions to access complex heterocyclic architectures.

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