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Atomfair 3-Bromo-5-chloropyridin-2-amine C5H4BrClN2

Description 3-Bromo-5-chloropyridin-2-amine (CAS No. 26163-03-1) is a high-purity halogenated pyridine derivative with the molecular formula C5H4BrClN2. This compound is a versatile building block in pharmaceutical and agrochemical research, featuring both bromo and chloro substituents on a pyridine ring with an amine group at the 2-position. Its unique structure enables selective functionalization for the synthesis of complex heterocycles. Available in >98% purity (HPLC), it is supplied as a crystalline solid with rigorous QC testing to ensure batch-to-batch consistency. Ideal for Suzuki couplings, nucleophilic substitutions, and metal-catalyzed cross-coupling reactions. Store under inert atmosphere at 2-8??C.

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Description

Description

3-Bromo-5-chloropyridin-2-amine (CAS No. 26163-03-1) is a high-purity halogenated pyridine derivative with the molecular formula C5H4BrClN2. This compound is a versatile building block in pharmaceutical and agrochemical research, featuring both bromo and chloro substituents on a pyridine ring with an amine group at the 2-position. Its unique structure enables selective functionalization for the synthesis of complex heterocycles. Available in >98% purity (HPLC), it is supplied as a crystalline solid with rigorous QC testing to ensure batch-to-batch consistency. Ideal for Suzuki couplings, nucleophilic substitutions, and metal-catalyzed cross-coupling reactions. Store under inert atmosphere at 2-8??C.

  • CAS No: 26163-03-1
  • Molecular Formula: C5H4BrClN2
  • Molecular Weight: 207.45
  • Exact Mass: 205.92464
  • Monoisotopic Mass: 205.92464
  • IUPAC Name: 3-bromo-5-chloropyridin-2-amine
  • SMILES: C1=C(C=NC(=C1Br)N)Cl
  • Synonyms: 3-bromo-5-chloropyridin-2-amine, 675-557-1, 2-Amino-3-bromo-5-chloropyridine, 26163-03-1, 2-Pyridinamine, 3-bromo-5-chloro-

Application

3-Bromo-5-chloropyridin-2-amine serves as a key intermediate in medicinal chemistry for developing kinase inhibitors and receptor modulators. Its halogenated pyridine core is utilized in palladium-catalyzed cross-coupling reactions to construct biaryl pharmacophores. Researchers employ this compound in the synthesis of patented antibacterial and antiviral agents. The presence of orthogonal halogen substituents enables sequential functionalization for structure-activity relationship studies.

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