Description

Description

3-Bromo-5-chlorobenzoic acid (CAS No. 42860-02-6) is a high-purity halogenated benzoic acid derivative with the molecular formula C₇H₄BrClO₂. This compound is a versatile building block in organic synthesis, featuring both bromo and chloro substituents on the aromatic ring, which enhance its reactivity in cross-coupling reactions and electrophilic substitutions. With a molecular weight of 235.46 g/mol, it is a white to off-white crystalline powder, soluble in organic solvents like DMSO, methanol, and dichloromethane but poorly soluble in water. Ideal for pharmaceutical intermediates, agrochemical research, and material science applications, this reagent is rigorously tested for purity (typically ??95% by HPLC or GC analysis) and is supplied with detailed analytical certificates. Store in a cool, dry place away from light to ensure stability.

Application

3-Bromo-5-chlorobenzoic acid is widely used as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals. Its halogenated aromatic structure makes it valuable for Suzuki-Miyaura and Buchwald-Hartwig coupling reactions in drug discovery. Researchers also employ it in the development of liquid crystals and organic electronic materials due to its electron-withdrawing properties. In agrochemical research, it serves as a precursor for herbicides and fungicides.

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