Description

(2S)-2-amino-6-((2,2,2-trifluoroacetyl)amino)hexanoic acid (CAS: 10009-20-8) is a high-purity, specialized amino acid derivative designed for advanced research and pharmaceutical applications. This compound, with the molecular formula C₈H₁₃F₃N₂O₃, features a trifluoroacetyl-protected lysine side chain, making it a valuable building block in peptide synthesis and proteomics studies. Its chiral purity (L-configuration) ensures compatibility with biological systems, while the trifluoroacetyl group enhances stability and reactivity in synthetic pathways. Ideal for researchers in medicinal chemistry, biochemistry, and drug development, this product is rigorously tested for quality and consistency, meeting the highest industry standards. Available in various quantities, it is supplied with detailed analytical data (HPLC, NMR, MS) to support your scientific endeavors.

Properties

• CAS Number: 10009-20-8
• Complexity: 255
• IUPAC Name: (2S)-2-amino-6-[(2,2,2-trifluoroacetyl)amino]hexanoic acid
• InChI: InChI=1S/C8H13F3N2O3/c9-8(10,11)7(16)13-4-2-1-3-5(12)6(14)15/h5H,1-4,12H2,(H,13,16)(H,14,15)/t5-/m0/s1
• InChI Key: PZZHRSVBHRVIMI-YFKPBYRVSA-N
• Exact Mass: 242.08782677
• Molecular Formula: C8H13F3N2O3
• Molecular Weight: 242.20
• SMILES: C(CCNC(=O)C(F)(F)F)C[C@@H](C(=O)O)N
• Topological: 92.4
• Monoisotopic Mass: 242.08782677
• Synonyms: L-Lysine, N6-(2,2,2-trifluoroacetyl)-, (2S)-2-amino-6-[(2,2,2-trifluoroacetyl)amino]hexanoic acid, N6-(2,2,2-trifluoroacetyl)-L-lysine, (2S)-2-amino-6-((2,2,2-trifluoroacetyl)amino)hexanoic acid, 600-027-3, 10009-20-8, H-Lys(Tfa)-OH, N-6-Trifluoroacetyl-L-lysine, N6-Trifluoroacetyl-L-lysine, N6-(Trifluoroacetyl)-L-lysine, Nepsilon-Trifluoroacetyl-L-lysine, Ne-Trifluoroacetyl-L-lysine, N(6)-trifluoroacetyl-L-lysine, L-Lysine, N6-(trifluoroacetyl)-, (S)-2-Amino-6-(2,2,2-trifluoroacetamido)hexanoic acid, CHEBI:61064, N(6)-(trifluoroacetyl)-L-lysine, L-Lys(Tfa)-OH, N6-Trifluoroaccety-L-lysine, (2S)-2-amino-6-(2,2,2-trifluoroacetylamino)hexanoic acid, TfAcK, e-TFA-lysine, n-epsilon-trifluoroacetyl-l-lysine, epsilon-TFA-lysine, (2S)-2-amino-6-(trifluoroacetamido)hexanoic acid, N6-(2,2,2-Trifluoroacetyl)-L-lysine; N6-(Trifluoroacetyl)lysine; Nepsilon-Trifluoroacetyl-L-lysine; N?-(Trifluoroacetyl)-L-lysine;, Lysine, N6-(trifluoroacetyl)-, L-, trifluoroacetyl lysine, 7E9HUX4XAD, Epitope ID:150923, N|A-Trifluoroacetyl-L-lysine, SCHEMBL875166, DTXSID70142926, N~6~-(trifluoroacetyl)-L-lysine, GLXC-25643, Nepsilon -trifluoroacetyl-L-lysine, SBB058284, AKOS015920404, AKOS015924094, AC-6228, CS-W012780, FN47703, HY-W012064, AS-12921, ST51016163, T2815, F10520, M06024, (S)-6-trifluoroacetylamino-2-aminohexanoic acid, EN300-7347469, (S)-6-(Trifluoroacetylamino)-2-aminohexanoic acid, Nepsilon-Trifluoroacetyl-L-lysine, >=96.0% (TLC), Q27130601

This compound is widely used as a protected lysine derivative in solid-phase peptide synthesis (SPPS), enabling selective deprotection strategies. It serves as a key intermediate in the development of peptide-based therapeutics and bioconjugates. Researchers also utilize it in post-translational modification studies and proteomics to investigate lysine acetylation dynamics. Its trifluoroacetyl group provides stability under acidic conditions, making it suitable for complex multi-step syntheses.

Safety and Hazards

GHS Hazard Statements

• Not Classified
• Reported as not meeting GHS hazard criteria by 1 of 1 companies. For more detailed information, please visit ECHA C&L website.

Hazard Classes and Categories

• Not Classified

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.