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Atomfair (2R,3S)-1-Boc-3-hydroxypyrrolidine-2-carbonitrile C10H16N2O3

Description (2R,3S)-1-Boc-3-hydroxypyrrolidine-2-carbonitrile (CAS No. 2227198-23-2) is a high-purity chiral building block extensively used in organic synthesis and pharmaceutical research. This compound features a tert -butyloxycarbonyl (Boc) protecting group, a hydroxyl group, and a nitrile functionality, making it a versatile intermediate for the preparation of complex molecules. With the molecular formula C10H16N2O3and IUPAC name tert -butyl 2-cyano-3-hydroxypyrrolidine-1-carboxylate, it is particularly valuable in asymmetric synthesis and medicinal chemistry applications. The (2R,3S) stereochemistry ensures precise control over enantioselective reactions. Available in >98% purity (HPLC), this product is rigorously tested for quality and stability, packaged under inert conditions to ensure long-term integrity.

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Description

Description

(2R,3S)-1-Boc-3-hydroxypyrrolidine-2-carbonitrile (CAS No. 2227198-23-2) is a high-purity chiral building block extensively used in organic synthesis and pharmaceutical research. This compound features a tert-butyloxycarbonyl (Boc) protecting group, a hydroxyl group, and a nitrile functionality, making it a versatile intermediate for the preparation of complex molecules. With the molecular formula C10H16N2O3 and IUPAC name tert-butyl 2-cyano-3-hydroxypyrrolidine-1-carboxylate, it is particularly valuable in asymmetric synthesis and medicinal chemistry applications. The (2R,3S) stereochemistry ensures precise control over enantioselective reactions. Available in >98% purity (HPLC), this product is rigorously tested for quality and stability, packaged under inert conditions to ensure long-term integrity.

  • CAS No: 2227198-23-2
  • Molecular Formula: C10H16N2O3
  • Molecular Weight: 212.25
  • Exact Mass: 212.11609238
  • Monoisotopic Mass: 212.11609238
  • IUPAC Name: tert-butyl 2-cyano-3-hydroxypyrrolidine-1-carboxylate
  • SMILES: CC(C)(C)OC(=O)N1CCC(C1C#N)O
  • Synonyms: MFCD29918581, PB41637, SY099338, (2R,3S)-1-Boc-3-hydroxypyrrolidine-2-carbonitrile

Application

(2R,3S)-1-Boc-3-hydroxypyrrolidine-2-carbonitrile serves as a key chiral synthon in the synthesis of bioactive compounds, including protease inhibitors and antiviral agents. Its hydroxyl and nitrile groups enable further functionalization via reduction, hydrolysis, or nucleophilic addition. The Boc group facilitates selective deprotection for downstream modifications. Researchers value this intermediate for constructing pyrrolidine-based scaffolds in drug discovery.

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