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Atomfair 2,6-Difluorophenylboronic acid C6H5BF2O2

Description 2,6-Difluorophenylboronic acid (CAS No. 162101-25-9) is a high-purity boronic acid derivative with the molecular formula C6H5BF2O2, widely utilized in organic synthesis and pharmaceutical research. This compound, also known as (2,6-difluorophenyl)boronic acid , features two fluorine atoms ortho to the boronic acid group, enhancing its reactivity in Suzuki-Miyaura cross-coupling reactions. Its crystalline structure and stability under inert conditions make it ideal for precise synthetic applications. Available in ??95% purity (HPLC), it is rigorously tested for moisture-sensitive storage requirements. Suitable for researchers in medicinal chemistry, material science, and catalysis, this reagent is packaged under argon to ensure longevity and performance.

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Description

Description

2,6-Difluorophenylboronic acid (CAS No. 162101-25-9) is a high-purity boronic acid derivative with the molecular formula C6H5BF2O2, widely utilized in organic synthesis and pharmaceutical research. This compound, also known as (2,6-difluorophenyl)boronic acid, features two fluorine atoms ortho to the boronic acid group, enhancing its reactivity in Suzuki-Miyaura cross-coupling reactions. Its crystalline structure and stability under inert conditions make it ideal for precise synthetic applications. Available in ??95% purity (HPLC), it is rigorously tested for moisture-sensitive storage requirements. Suitable for researchers in medicinal chemistry, material science, and catalysis, this reagent is packaged under argon to ensure longevity and performance.

  • CAS No: 162101-25-9
  • Molecular Formula: C6H5BF2O2
  • Molecular Weight: 157.91
  • Exact Mass: 158.0350659
  • Monoisotopic Mass: 158.0350659
  • IUPAC Name: (2,6-difluorophenyl)boronic acid
  • SMILES: B(C1=C(C=CC=C1F)F)(O)O
  • Synonyms: 2,6-Difluorophenylboronic acid, 162101-25-9, diorthofluorophenylboronic acid, DTXSID70370227, DTXCID60321263

Application

2,6-Difluorophenylboronic acid is a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of biaryl compounds for pharmaceuticals and agrochemicals. Its ortho-fluorine substitution pattern enhances steric and electronic effects in catalytic systems. Researchers also employ it in the development of boron-based sensors and functional materials. The compound’s stability and reactivity make it valuable for constructing complex molecular architectures in drug discovery.

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