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Atomfair 2,4,5-Trifluoro-3-methoxybenzoyl chloride C8H4ClF3O2

Description 2,4,5-Trifluoro-3-methoxybenzoyl chloride (CAS No. 1187318-54-2) is a high-purity, fluorinated benzoyl chloride derivative with the molecular formula C8H4ClF3O2. This reactive intermediate is widely utilized in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and advanced materials. Its unique trifluoro-methoxy substitution pattern enhances electrophilic reactivity, making it ideal for acylations and coupling reactions. The compound is supplied as a clear to pale-yellow liquid under inert conditions to ensure stability. Suitable for use in controlled environments, it is packaged in amber glass vials or sealed ampoules to prevent moisture degradation. Store at 2-8??C under anhydrous conditions.

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Description

Description

2,4,5-Trifluoro-3-methoxybenzoyl chloride (CAS No. 1187318-54-2) is a high-purity, fluorinated benzoyl chloride derivative with the molecular formula C8H4ClF3O2. This reactive intermediate is widely utilized in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and advanced materials. Its unique trifluoro-methoxy substitution pattern enhances electrophilic reactivity, making it ideal for acylations and coupling reactions. The compound is supplied as a clear to pale-yellow liquid under inert conditions to ensure stability. Suitable for use in controlled environments, it is packaged in amber glass vials or sealed ampoules to prevent moisture degradation. Store at 2-8??C under anhydrous conditions.

  • CAS No: 1187318-54-2
  • Molecular Formula: C8H4ClF3O2
  • Molecular Weight: 224.56
  • Exact Mass: 223.9851915
  • Monoisotopic Mass: 223.9851915
  • IUPAC Name: 2,4,5-trifluoro-3-methoxybenzoyl chloride
  • SMILES: COC1=C(C(=CC(=C1F)F)C(=O)Cl)F
  • Synonyms: 2,4,5-Trifluoro-3-methoxybenzoyl chloride, 112811-66-2, DTXSID90379494, DTXCID90330520, 629-469-5

Application

2,4,5-Trifluoro-3-methoxybenzoyl chloride serves as a key building block in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and specialty chemicals. Its reactivity enables efficient acylation of amines and alcohols to form amides or esters, respectively. Researchers employ it in the development of herbicides and fungicides due to its bioactivity-enhancing fluorine motifs. The compound is also used in material science for modifying polymer backbones to impart hydrophobicity and chemical resistance.

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