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Atomfair 2,4-Dihydro-2-methyl-5-(trifluoromethyl)-3H-pyrazol-3-one C5H5F3N2O

Description 2,4-Dihydro-2-methyl-5-(trifluoromethyl)-3H-pyrazol-3-one (CAS No. 122431-37-2) is a high-purity fluorinated pyrazolone derivative with the molecular formula C5H5F3N2O . This compound, also known by its IUPAC name 2-methyl-5-(trifluoromethyl)-4H-pyrazol-3-one , is a versatile heterocyclic building block widely used in pharmaceutical, agrochemical, and materials science research. Its unique trifluoromethyl group enhances lipophilicity and metabolic stability, making it valuable for structure-activity relationship (SAR) studies. Available in ??98% purity (HPLC), this reagent is supplied as a white to off-white crystalline powder with strict quality control to ensure batch-to-batch consistency. Store in a cool, dry place under inert atmosphere for optimal stability. Suitable for nucleophilic substitution reactions,…

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Description

Description

2,4-Dihydro-2-methyl-5-(trifluoromethyl)-3H-pyrazol-3-one (CAS No. 122431-37-2) is a high-purity fluorinated pyrazolone derivative with the molecular formula C5H5F3N2O. This compound, also known by its IUPAC name 2-methyl-5-(trifluoromethyl)-4H-pyrazol-3-one, is a versatile heterocyclic building block widely used in pharmaceutical, agrochemical, and materials science research. Its unique trifluoromethyl group enhances lipophilicity and metabolic stability, making it valuable for structure-activity relationship (SAR) studies. Available in ??98% purity (HPLC), this reagent is supplied as a white to off-white crystalline powder with strict quality control to ensure batch-to-batch consistency. Store in a cool, dry place under inert atmosphere for optimal stability. Suitable for nucleophilic substitution reactions, metal-catalyzed cross-couplings, and as a precursor for bioactive molecule synthesis.

  • CAS No: 122431-37-2
  • Molecular Formula: C5H5F3N2O
  • Molecular Weight: 166.10
  • Exact Mass: 166.03539727
  • Monoisotopic Mass: 166.03539727
  • IUPAC Name: 2-methyl-5-(trifluoromethyl)-4H-pyrazol-3-one
  • SMILES: CN1C(=O)CC(=N1)C(F)(F)F
  • Synonyms: 1481-02-3, 1-Methyl-3-trifluoromethyl-2-pyrazolin-5-one, DTXSID70333791, 2,4-Dihydro-2-methyl-5-(trifluoromethyl)-3H-pyrazol-3-one, DTXCID80284881

Application

This trifluoromethyl-substituted pyrazolone is primarily employed as a key intermediate in the synthesis of pharmaceuticals, particularly for developing anti-inflammatory and antimicrobial agents. Its electron-withdrawing trifluoromethyl group facilitates the creation of metabolically stable drug candidates. Researchers also utilize it in agrochemical formulations to enhance pesticide efficacy. In materials science, it serves as a precursor for specialty polymers with improved thermal and chemical resistance.

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