Atomfair

Awaiting product image

Atomfair 2-(Trifluoromethoxy)aniline C7H6F3NO

Description 2-(Trifluoromethoxy)aniline (CAS No. 1535-75-7) is a high-purity aromatic amine derivative with the molecular formula C7H6F3NO . This compound features a trifluoromethoxy (-OCF3) group ortho to an amino (-NH2) substituent on a benzene ring, offering unique electronic and steric properties for advanced synthetic applications. With a molecular weight of 177.12 g/mol, it is a versatile building block in pharmaceutical, agrochemical, and materials science research. Our product is rigorously tested to ensure ??98% purity (GC) and is supplied in sealed, light-resistant containers to maintain stability. Ideal for nucleophilic substitutions, cross-coupling reactions, and as a precursor for heterocyclic compounds.

Category:
Brands:

Description

Description

2-(Trifluoromethoxy)aniline (CAS No. 1535-75-7) is a high-purity aromatic amine derivative with the molecular formula C7H6F3NO. This compound features a trifluoromethoxy (-OCF3) group ortho to an amino (-NH2) substituent on a benzene ring, offering unique electronic and steric properties for advanced synthetic applications. With a molecular weight of 177.12 g/mol, it is a versatile building block in pharmaceutical, agrochemical, and materials science research. Our product is rigorously tested to ensure ??98% purity (GC) and is supplied in sealed, light-resistant containers to maintain stability. Ideal for nucleophilic substitutions, cross-coupling reactions, and as a precursor for heterocyclic compounds.

  • CAS No: 1535-75-7
  • Molecular Formula: C7H6F3NO
  • Molecular Weight: 177.12
  • Exact Mass: 177.04014830
  • Monoisotopic Mass: 177.04014830
  • IUPAC Name: 2-(trifluoromethoxy)aniline
  • SMILES: C1=CC=C(C(=C1)N)OC(F)(F)F
  • Synonyms: 2-(Trifluoromethoxy)aniline, 1535-75-7, 2-trifluoromethoxyaniline, EINECS 216-257-9, DTXSID20165342

Application

2-(Trifluoromethoxy)aniline is widely used as a key intermediate in the synthesis of bioactive molecules, particularly in pharmaceuticals and crop protection agents. Its electron-withdrawing trifluoromethoxy group enhances the reactivity of the aniline moiety in palladium-catalyzed couplings (e.g., Buchwald-Hartwig amination). Researchers also employ it to develop liquid crystals and OLED materials due to its unique polarizability. In medicinal chemistry, it serves as a scaffold for kinase inhibitors and CNS-targeting compounds.

If you are interested or have any questions, please contact us at support@atomfair.com