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Atomfair 2-Iodoadenosine C10H12IN5O4

Description 2-Iodoadenosine (CAS No. 35109-88-7) is a modified nucleoside analog featuring an iodine substitution at the 2-position of the adenine base. With the molecular formula C10H12IN5O4and IUPAC name (2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol , this compound is a valuable biochemical tool for research applications. It is commonly used in nucleoside chemistry, enzyme studies, and as a precursor for further derivatization. The iodine moiety enhances its reactivity, making it suitable for cross-coupling reactions and radiolabeling. This high-purity compound is supplied as a crystalline solid with >95% purity (HPLC), ensuring reliability for sensitive experimental workflows. Store at -20??C under inert conditions to maintain stability.

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Description

Description

2-Iodoadenosine (CAS No. 35109-88-7) is a modified nucleoside analog featuring an iodine substitution at the 2-position of the adenine base. With the molecular formula C10H12IN5O4 and IUPAC name (2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, this compound is a valuable biochemical tool for research applications. It is commonly used in nucleoside chemistry, enzyme studies, and as a precursor for further derivatization. The iodine moiety enhances its reactivity, making it suitable for cross-coupling reactions and radiolabeling. This high-purity compound is supplied as a crystalline solid with >95% purity (HPLC), ensuring reliability for sensitive experimental workflows. Store at -20??C under inert conditions to maintain stability.

  • CAS No: 35109-88-7
  • Molecular Formula: C10H12IN5O4
  • Molecular Weight: 393.14
  • Exact Mass: 392.99340
  • Monoisotopic Mass: 392.99340
  • IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
  • SMILES: C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)I)N
  • Synonyms: 2-Iodoadenosine, 35109-88-7, Adenosine, 2-iodo-, DTXSID70188607, DTXCID90111098

Application

2-Iodoadenosine is widely utilized in biochemical research as a precursor for synthesizing modified nucleosides and nucleotides. It serves as a key intermediate in the study of adenosine receptor interactions and enzyme mechanisms, particularly in purine metabolism pathways. Researchers also employ it in radiolabeling and cross-coupling reactions for probe development. Its iodine substitution enables versatile applications in medicinal chemistry and drug discovery.

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