Description

Description

2-Fluoroacetanilide (CAS No. 399-31-5) is a high-purity fluorinated organic compound with the molecular formula C₈H₈FNO and the IUPAC name 2-fluoro-N-phenylacetamide. This white to off-white crystalline powder is a valuable intermediate in pharmaceutical and agrochemical research, offering exceptional reactivity for selective fluorination reactions. With a molecular weight of 153.15 g/mol, it is characterized by its stability under standard laboratory conditions and compatibility with a wide range of organic solvents. Our product is rigorously tested to ensure ??98% purity (HPLC) and is supplied with comprehensive analytical documentation including ¹H NMR, ¹³C NMR, and mass spectrometry data. Ideal for medicinal chemistry applications, this compound is packaged under inert atmosphere in amber glass vials to ensure long-term stability.

Key Specifications:

• CAS: 399-31-5 / 330-68-7 (alternative)
• Purity: ??98% (HPLC)
• Melting Point: 92-96??C
• Storage: 2-8??C in dry conditions
• Hazard Codes: Xi (Irritant)

Application

2-Fluoroacetanilide serves as a versatile building block in pharmaceutical research, particularly in the synthesis of fluorinated drug candidates where the introduction of fluorine atoms can significantly alter bioavailability and metabolic stability. This compound is frequently employed in palladium-catalyzed cross-coupling reactions for constructing complex heterocyclic scaffolds. Researchers utilize it as a precursor for developing PET radiotracers due to the favorable nuclear properties of fluorine-18. In material science, it finds application as a monomer for specialty polymers with enhanced thermal resistance.

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