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Atomfair 2-Fluoro-5-methylaniline C7H8FN

Description 2-Fluoro-5-methylaniline (CAS No. 443-89-0) is a high-purity fluorinated aromatic amine with the molecular formula C7H8FN . This compound is a valuable intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its structure features a fluorine atom at the ortho position and a methyl group at the meta position relative to the amino group, offering unique reactivity for selective functionalization. Available in >98% purity (GC), it is supplied as a clear to pale yellow liquid with strict quality control to ensure consistency for research and industrial applications. Ideal for Suzuki couplings, diazotization, and other nucleophilic aromatic substitution reactions.…

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Description

Description

2-Fluoro-5-methylaniline (CAS No. 443-89-0) is a high-purity fluorinated aromatic amine with the molecular formula C7H8FN. This compound is a valuable intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its structure features a fluorine atom at the ortho position and a methyl group at the meta position relative to the amino group, offering unique reactivity for selective functionalization. Available in >98% purity (GC), it is supplied as a clear to pale yellow liquid with strict quality control to ensure consistency for research and industrial applications. Ideal for Suzuki couplings, diazotization, and other nucleophilic aromatic substitution reactions. Store under inert atmosphere at 2-8??C to maintain stability.

  • CAS No: 443-89-0
  • Molecular Formula: C7H8FN
  • Molecular Weight: 125.14
  • Exact Mass: 125.064077422
  • Monoisotopic Mass: 125.064077422
  • IUPAC Name: 2-fluoro-5-methylaniline
  • SMILES: CC1=CC(=C(C=C1)F)N
  • Synonyms: 2-Fluoro-5-methylaniline, 452-84-6, 6-Fluoro-m-toluidine, Benzenamine, 2-fluoro-5-methyl-, QZUXMXZNVAJNSE-UHFFFAOYSA-

Application

2-Fluoro-5-methylaniline is widely used as a building block in the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals. It serves as a precursor for fluorinated heterocycles in drug discovery, particularly in kinase inhibitors and antimicrobial agents. The compound’s reactivity also makes it suitable for developing liquid crystal materials and agrochemical intermediates. Its orthogonal functional groups enable modular derivatization for combinatorial chemistry workflows.

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