Atomfair

Awaiting product image

Atomfair 2-Fluoro-4-iodopyridine C5H3FIN

Description 2-Fluoro-4-iodopyridine (CAS No. 22282-70-8) is a high-purity halogenated pyridine derivative with the molecular formula C5H3FIN . This compound is a versatile building block in pharmaceutical, agrochemical, and materials science research, offering unique reactivity due to the synergistic effects of fluorine and iodine substituents on the pyridine ring. Its IUPAC name, 2-fluoro-4-iodopyridine , reflects its precise structural configuration. Available in >98% purity (HPLC), this product is rigorously tested for consistency and stability, making it ideal for nucleophilic substitution reactions, cross-coupling reactions (e.g., Suzuki-Miyaura, Stille), and as a precursor for advanced heterocyclic systems. Packaged under inert gas to prevent degradation, each…

Category:
Brands:

Description

Description

2-Fluoro-4-iodopyridine (CAS No. 22282-70-8) is a high-purity halogenated pyridine derivative with the molecular formula C5H3FIN. This compound is a versatile building block in pharmaceutical, agrochemical, and materials science research, offering unique reactivity due to the synergistic effects of fluorine and iodine substituents on the pyridine ring. Its IUPAC name, 2-fluoro-4-iodopyridine, reflects its precise structural configuration. Available in >98% purity (HPLC), this product is rigorously tested for consistency and stability, making it ideal for nucleophilic substitution reactions, cross-coupling reactions (e.g., Suzuki-Miyaura, Stille), and as a precursor for advanced heterocyclic systems. Packaged under inert gas to prevent degradation, each batch includes comprehensive analytical data (GC/MS, 1H/13C NMR).

  • CAS No: 22282-70-8
  • Molecular Formula: C5H3FIN
  • Molecular Weight: 222.99
  • Exact Mass: 222.92942
  • Monoisotopic Mass: 222.92942
  • IUPAC Name: 2-fluoro-4-iodopyridine
  • SMILES: C1=CN=C(C=C1I)F
  • Synonyms: 2-Fluoro-4-iodopyridine, 22282-70-8, DTXSID80427514, DTXCID10378348, 681-832-7

Application

2-Fluoro-4-iodopyridine serves as a critical intermediate in medicinal chemistry for the synthesis of fluorinated drug candidates, particularly kinase inhibitors and CNS-targeting molecules. Its iodine moiety facilitates palladium-catalyzed cross-coupling reactions to construct complex biaryl structures, while the fluorine enhances metabolic stability. In materials science, it is employed in the development of liquid crystals and organic semiconductors. Researchers also utilize it to introduce fluorine tags for 19F NMR studies.

If you are interested or have any questions, please contact us at support@atomfair.com