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Atomfair 2-Cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Cyclopropylboronic acid pinacol ester C9H17BO2

Description 2-Cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS No. 126689-01-8) is a high-purity boronic ester compound with the molecular formula C9H17BO2. This organoboron reagent, also known as Cyclopropylboronic acid pinacol ester , is widely utilized in Suzuki-Miyaura cross-coupling reactions due to its stability and reactivity. The cyclopropyl moiety enhances its utility in the synthesis of complex pharmaceutical intermediates and agrochemicals. Our product is rigorously tested to ensure >98% purity (GC), with stringent quality control for moisture and heavy metal content. Supplied in amber glass vials under inert gas to prevent degradation, it is ideal for sensitive synthetic applications.

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Description

Description

2-Cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS No. 126689-01-8) is a high-purity boronic ester compound with the molecular formula C9H17BO2. This organoboron reagent, also known as Cyclopropylboronic acid pinacol ester, is widely utilized in Suzuki-Miyaura cross-coupling reactions due to its stability and reactivity. The cyclopropyl moiety enhances its utility in the synthesis of complex pharmaceutical intermediates and agrochemicals. Our product is rigorously tested to ensure >98% purity (GC), with stringent quality control for moisture and heavy metal content. Supplied in amber glass vials under inert gas to prevent degradation, it is ideal for sensitive synthetic applications.

  • CAS No: 126689-01-8
  • Molecular Formula: C9H17BO2
  • Molecular Weight: 168.04
  • Exact Mass: 168.1321599
  • Monoisotopic Mass: 168.1321599
  • IUPAC Name: 2-cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2CC2
  • Synonyms: 126689-01-8, 2-Cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, Cyclopropylboronic acid pinacol ester, DTXSID50374127, DTXCID90325158

Application

2-Cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a key intermediate in palladium-catalyzed cross-coupling reactions, enabling the introduction of cyclopropyl groups into aromatic systems. It is particularly valuable in medicinal chemistry for constructing cyclopropyl-containing bioactive molecules, such as protease inhibitors and CNS-targeting drugs. The compound’s stability under basic conditions makes it suitable for multi-step synthetic workflows.

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