Description
2-Chloro-p-toluidine (CAS No. 615-65-6), also known as 2-chloro-4-methylaniline, is a high-purity organic compound with the molecular formula C7H8ClN. This aromatic amine is characterized by a chlorine substituent at the ortho position and a methyl group at the para position relative to the amino functional group. It is a versatile intermediate widely used in pharmaceutical synthesis, agrochemical production, and dye manufacturing. Our product is rigorously tested to ensure superior quality, with HPLC purity ≥98%, and is supplied as a crystalline solid or powder. Proper handling under inert conditions is recommended due to its sensitivity to oxidation. Ideal for researchers in organic chemistry, medicinal chemistry, and material science applications.
Properties
- CAS Number: 615-65-6
- Complexity: 94.9
- IUPAC Name: 2-chloro-4-methyl-aniline
- InChI: InChI=1S/C7H8ClN/c1-5-2-3-7(9)6(8)4-5/h2-4H,9H2,1H3
- InChI Key: XGYLSRFSXKAYCR-UHFFFAOYSA-N
- Exact Mass: 141.0345270
- Molecular Formula: C7H8ClN
- Molecular Weight: 141.60
- SMILES: CC1=CC(=C(C=C1)N)Cl
- Topological: 26
- Monoisotopic Mass: 141.0345270
- Physical Description: Pale yellow liquid;
- Boiling Point: 219 °C @ 732 MM HG
- Melting Point: 7 °C
- Solubility: SLIGHTLY SOL IN WATER, ACETONE
- Density: 1.151 @ 20 °C
- Refractive Index: INDEX OF REFRACTION: 1.5748 @ 22 °C/D
- Synonyms: 2-Chloro-4-methylaniline, 615-65-6, 2-CHLORO-P-TOLUIDINE, Benzenamine, 2-chloro-4-methyl-, 4-Amino-3-chlorotoluene, p-Toluidine, 2-chloro-, 4-Methyl-2-chloroaniline, 2-Chlor-4-toluidin, NSC 60120, 2-Chlor-4-toluidin [Czech], CCRIS 2887, HSDB 2059, 3-Chloro-4-aminotoluene, 1-amino-2-chloro-4-methylbenzene, EINECS 210-440-7, K59ISJ2KO1, BRN 0774514, NSC-60120, DTXSID3022083, 3-12-00-02152 (Beilstein Handbook Reference), 2-CHLORO-P-TOLUIDINE [HSDB], (2-CHLORO-4-METHYLPHENYL)AMINE, 2-CHLOR-4-TOLUIDIN (CZECH), 2Chlor4toluidin, pToluidine, 2chloro, 2Chloro4methylaniline, 4Methyl2chloroaniline, Benzenamine, 2chloro4methyl, DTXCID802083, UN3429, 210-440-7, inchi=1/c7h8cln/c1-5-2-3-7(9)6(8)4-5/h2-4h,9h2,1h, 2-chloro-4-methyl-aniline, MFCD00007666, 2-chloro-4-methylphenylamine, UNII-K59ISJ2KO1, 2-chloro-4-methyl aniline, 2-CHLORO-4-METHYLANILINE HYDROCHLORIDE, 2-Chloro-4-methyl-phenylamine, NSC60120, 2-Chlor-p-toluidin, 2-choro-4-methylaniline, 4-amino-3-chloro-toluene, 2-Chloro-4-methylbenzamine, WLN: ZR BG D1, 2-chloro-4-methylbenzenamine, 2-chloranyl-4-methyl-aniline, SCHEMBL172051, SCHEMBL1802334, SCHEMBL2955980, SCHEMBL5731995, SCHEMBL5961697, SCHEMBL15966950, 2-Chloro-4-methylaniline, 98%, STL163411, AKOS000113146, CCG-302526, CS-W018296, FC05832, PS-3795, NCGC00166060-01, AC-23555, SY013538, DB-024170, A8535, NS00005065, ST50823757, EN300-19674, A833307, Q27281976, F0001-1625, Z104474672
Application
2-Chloro-p-toluidine serves as a key intermediate in the synthesis of azo dyes and pigments, contributing to vibrant colorants for textiles and plastics. In pharmaceuticals, it is utilized in the preparation of active pharmaceutical ingredients (APIs) and fine chemicals. Additionally, it finds application in agrochemical research for developing herbicides and pesticides. Its reactivity as an aromatic amine makes it valuable in cross-coupling reactions and heterocyclic compound synthesis.
Safety and Hazards
GHS Hazard Statements
- H302+H312+H332 (86.7%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]
- H302 (95.6%): Harmful if swallowed [Warning Acute toxicity, oral]
- H312 (95.6%): Harmful in contact with skin [Warning Acute toxicity, dermal]
- H315 (97.8%): Causes skin irritation [Warning Skin corrosion/irritation]
- H318 (86.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
- H319 (11.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H332 (95.6%): Harmful if inhaled [Warning Acute toxicity, inhalation]
- H412 (86.7%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
Precautionary Statements
- P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P321, P330, P332+P317, P337+P317, P362+P364, and P501
Hazard Classes and Categories
- Acute Tox. 4 (95.6%)
- Acute Tox. 4 (95.6%)
- Skin Irrit. 2 (97.8%)
- Eye Dam. 1 (86.7%)
- Eye Irrit. 2 (11.1%)
- Acute Tox. 4 (95.6%)
- Aquatic Chronic 3 (86.7%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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