Atomfair 2-Chloro-3-fluoro-5-methylpyridine C6H5ClFN

Description 2-Chloro-3-fluoro-5-methylpyridine (CAS No. 21324-40-3) is a high-purity halogenated pyridine derivative with the molecular formula C6H5ClFN . This compound is a versatile intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its unique structure, featuring chloro, fluoro, and methyl substituents on the pyridine ring, enables selective functionalization for the development of advanced molecules. Available in >98% purity (GC), it is supplied in sealed, light-resistant packaging under inert gas to ensure stability. Ideal for researchers requiring precise heterocyclic building blocks for cross-coupling reactions, nucleophilic substitutions, or catalyst design. MSDS and analytical data (NMR, HPLC) available upon request.

Description

2-Chloro-3-fluoro-5-methylpyridine (CAS No. 21324-40-3) is a high-purity halogenated pyridine derivative with the molecular formula C₆H₅ClFN. This compound is a versatile intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its unique structure, featuring chloro, fluoro, and methyl substituents on the pyridine ring, enables selective functionalization for the development of advanced molecules. Available in >98% purity (GC), it is supplied in sealed, light-resistant packaging under inert gas to ensure stability. Ideal for researchers requiring precise heterocyclic building blocks for cross-coupling reactions, nucleophilic substitutions, or catalyst design. MSDS and analytical data (NMR, HPLC) available upon request.

CAS No: 21324-40-3
Molecular Formula: C6H5ClFN
Molecular Weight: 145.56
Exact Mass: 145.0094550
Monoisotopic Mass: 145.0094550
IUPAC Name: 2-chloro-3-fluoro-5-methylpyridine
SMILES: CC1=CC(=C(N=C1)Cl)F
Synonyms: 2-chloro-3-fluoro-5-methylpyridine, 34552-15-3, DTXSID80543283, DTXCID20494068, 675-593-8

Application

2-Chloro-3-fluoro-5-methylpyridine serves as a key intermediate in synthesizing active pharmaceutical ingredients (APIs) and crop protection agents. Its electron-deficient pyridine core facilitates Suzuki-Miyaura and Buchwald-Hartwig couplings for drug discovery. The compound’s fluorine moiety enhances metabolic stability in bioactive molecules, while the chloro group allows further derivatization. Researchers utilize it in developing kinase inhibitors and herbicides.

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