Description

Description

2-Bromo-5-fluoro-3-nitrobenzoic acid (CAS No. 1153279-80-1) is a high-purity aromatic carboxylic acid derivative designed for advanced synthetic and pharmaceutical research applications. This compound features a molecular formula of C₇H₃BrFNO₄ and a molecular weight of 263.99 g/mol, with a precise structural configuration comprising bromo, fluoro, and nitro functional groups ortho and meta to the carboxylic acid moiety. Its crystalline solid form ensures excellent handling stability, while its reactivity makes it a versatile intermediate in heterocyclic synthesis, cross-coupling reactions, and medicinal chemistry. Ideal for researchers requiring regioselective functionalization, this product is rigorously tested via HPLC, NMR, and MS to guarantee ??95% purity, meeting stringent laboratory standards. Packaged under inert conditions to prevent degradation, it is supplied in amber glass vials with tamper-evident seals for optimal shelf life.

Application

2-Bromo-5-fluoro-3-nitrobenzoic acid serves as a critical building block in the synthesis of fluorinated pharmaceuticals, agrochemicals, and specialty materials. Its reactive bromo and nitro groups facilitate Suzuki-Miyaura and Buchwald-Hartwig couplings, enabling the construction of complex biaryl scaffolds. Researchers utilize this compound in the development of kinase inhibitors and PET radiotracers due to its fluorine moiety. It also finds use in material science for designing nitroaromatic-based polymers with tailored electronic properties.

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