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Atomfair 2-Bromo-1-(2,5-difluorophenyl)ethanone C8H5BrF2O
Description 2-Bromo-1-(2,5-difluorophenyl)ethanone (CAS No. 258513-41-6) is a high-purity brominated difluorophenyl ketone derivative with the molecular formula C8H5BrF2O. This compound is a versatile building block in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and advanced materials. Its unique structure, featuring both bromine and fluorine substituents, makes it an ideal intermediate for nucleophilic substitution reactions, cross-coupling reactions, and other functional group transformations. The product is supplied as a crystalline solid with ??98% purity (HPLC), ensuring consistency for research and industrial applications. Proper handling under inert conditions is recommended due to its sensitivity to moisture and light. Available in scalable quantities…
Description
Description
2-Bromo-1-(2,5-difluorophenyl)ethanone (CAS No. 258513-41-6) is a high-purity brominated difluorophenyl ketone derivative with the molecular formula C8H5BrF2O. This compound is a versatile building block in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and advanced materials. Its unique structure, featuring both bromine and fluorine substituents, makes it an ideal intermediate for nucleophilic substitution reactions, cross-coupling reactions, and other functional group transformations. The product is supplied as a crystalline solid with ??98% purity (HPLC), ensuring consistency for research and industrial applications. Proper handling under inert conditions is recommended due to its sensitivity to moisture and light. Available in scalable quantities with comprehensive analytical data (NMR, MS, HPLC) for quality assurance.
- CAS No: 258513-41-6
- Molecular Formula: C8H5BrF2O
- Molecular Weight: 235.02
- Exact Mass: 233.94918
- Monoisotopic Mass: 233.94918
- IUPAC Name: 2-bromo-1-(2,5-difluorophenyl)ethanone
- SMILES: C1=CC(=C(C=C1F)C(=O)CBr)F
- Synonyms: 258513-41-6, 2-bromo-1-(2,5-difluorophenyl)ethanone, 2,5-DIFLUOROPHENACYL BROMIDE, 2-Bromo-2′,5′-difluoroacetophenone, 2-Bromo-1-(2,5-Difluorophenyl)Ethan-1-One
Application
2-Bromo-1-(2,5-difluorophenyl)ethanone is widely used as a key intermediate in the synthesis of bioactive molecules, including kinase inhibitors and fluorinated pharmaceuticals. Its reactivity enables efficient incorporation of the 2,5-difluorophenyl moiety into complex scaffolds for drug discovery. The compound is also employed in material science for developing liquid crystals and OLED materials due to its electron-withdrawing properties. Researchers utilize it in palladium-catalyzed cross-coupling reactions to construct aryl-aryl bonds in medicinal chemistry.
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