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Atomfair (2-BOC-aminophenyl)boronic acid C11H16BNO4

Description (2-BOC-aminophenyl)boronic acid (CAS: 115377-94-1) is a high-purity boronic acid derivative featuring a tert-butoxycarbonyl (BOC)-protected amine group at the ortho position of the phenyl ring. With the molecular formula C11H16BNO4, this compound is a valuable intermediate in organic synthesis , particularly in Suzuki-Miyaura cross-coupling reactions, where it serves as a versatile boron-containing coupling partner. The BOC group enhances stability, making it ideal for peptide synthesis and pharmaceutical research. This product is supplied as a white to off-white crystalline powder with ??95% purity (HPLC), ensuring consistent performance in sensitive applications. Store in a cool, dry place under inert conditions to maintain…

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Description

Description

(2-BOC-aminophenyl)boronic acid (CAS: 115377-94-1) is a high-purity boronic acid derivative featuring a tert-butoxycarbonyl (BOC)-protected amine group at the ortho position of the phenyl ring. With the molecular formula C11H16BNO4, this compound is a valuable intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, where it serves as a versatile boron-containing coupling partner. The BOC group enhances stability, making it ideal for peptide synthesis and pharmaceutical research. This product is supplied as a white to off-white crystalline powder with ??95% purity (HPLC), ensuring consistent performance in sensitive applications. Store in a cool, dry place under inert conditions to maintain integrity.

  • CAS No: 115377-94-1
  • Molecular Formula: C11H16BNO4
  • Molecular Weight: 237.06
  • Exact Mass: 237.1172382
  • Monoisotopic Mass: 237.1172382
  • IUPAC Name: [2-[(2-methylpropan-2-yl)oxycarbonylamino]phenyl]boronic acid
  • SMILES: B(C1=CC=CC=C1NC(=O)OC(C)(C)C)(O)O
  • Synonyms: (2-BOC-AMINOPHENYL)BORONIC ACID, 640-451-6, 115377-94-1, 2-BOC-aminophenylboronic acid, (2-((tert-Butoxycarbonyl)amino)phenyl)boronic acid

Application

(2-BOC-aminophenyl)boronic acid is widely used in medicinal chemistry for the synthesis of biologically active compounds, including protease inhibitors and kinase-targeting drugs. It serves as a key building block in peptide coupling and protecting group strategies due to its orthogonal reactivity. Researchers also employ it in metal-catalyzed cross-coupling reactions to construct biaryl scaffolds for drug discovery and materials science.

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