Description

Description

2-(2-Amino-5-fluorophenyl)acetic acid (CAS No. 1195768-18-3) is a high-purity fluorinated aromatic compound with the molecular formula C₈H₈FNO₂. This white to off-white crystalline powder is a valuable building block in pharmaceutical and agrochemical research, offering a unique combination of an amino group and a carboxylic acid functional group on a fluorinated benzene ring. With a molecular weight of 169.15 g/mol, this compound is soluble in common organic solvents such as DMSO, methanol, and ethanol, but has limited solubility in water. Its purity is typically ??95% by HPLC, making it suitable for demanding synthetic applications. The compound is supplied in amber glass vials under inert atmosphere to ensure stability and longevity. Proper storage at 2-8??C is recommended to maintain product integrity.

Application

2-(2-Amino-5-fluorophenyl)acetic acid serves as a key intermediate in the synthesis of various bioactive molecules, particularly in the development of novel pharmaceuticals targeting CNS disorders. The compound’s fluorinated aromatic structure makes it valuable for creating PET radiotracers in medical imaging applications. Researchers utilize this building block in the preparation of potential kinase inhibitors and other small molecule therapeutics. The presence of both amino and carboxylic acid functional groups allows for versatile derivatization through amide coupling or other conjugation reactions.

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