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Atomfair 1-Methyl-5-(3-azido-2,3-dideoxy-beta-pentofuranosyl)uracil C-AZT, 1-Me-5(3-Az-ddribo)T C10H13N5O4

Description 1-Methyl-5-(3-azido-2,3-dideoxy-beta-pentofuranosyl)uracil (CAS No. 127523-43-7) is a specialized nucleoside analog with the molecular formula C10H13N5O4. This compound, also known by its IUPAC name 5-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-1-methylpyrimidine-2,4-dione , features a modified uracil base attached to a pentofuranosyl ring with an azido group at the 3′ position. It is a valuable intermediate in medicinal chemistry and biochemical research, particularly in the study of antiviral and antiretroviral agents. The compound is supplied as a high-purity solid, rigorously tested for quality and consistency, making it ideal for research applications requiring precise and reliable reagents.

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Description

Description

1-Methyl-5-(3-azido-2,3-dideoxy-beta-pentofuranosyl)uracil (CAS No. 127523-43-7) is a specialized nucleoside analog with the molecular formula C10H13N5O4. This compound, also known by its IUPAC name 5-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-1-methylpyrimidine-2,4-dione, features a modified uracil base attached to a pentofuranosyl ring with an azido group at the 3′ position. It is a valuable intermediate in medicinal chemistry and biochemical research, particularly in the study of antiviral and antiretroviral agents. The compound is supplied as a high-purity solid, rigorously tested for quality and consistency, making it ideal for research applications requiring precise and reliable reagents.

  • CAS No: 127523-43-7
  • Molecular Formula: C10H13N5O4
  • Molecular Weight: 267.24
  • Exact Mass: 267.09675391
  • Monoisotopic Mass: 267.09675391
  • IUPAC Name: 5-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-1-methylpyrimidine-2,4-dione
  • SMILES: CN1C=C(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-]
  • Synonyms: 127517-38-8, 1-Methyl-5-(3-azido-2,3-dideoxy-beta-pentofuranosyl)uracil, C-AZT, 5-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-1-methylpyrimidine-2,4-dione, 1-Me-5(3-Az-ddribo)T

Application

1-Methyl-5-(3-azido-2,3-dideoxy-beta-pentofuranosyl)uracil is primarily used in the development of nucleoside analogs for antiviral research. It serves as a key intermediate in the synthesis of modified nucleosides that may exhibit activity against retroviruses. Researchers utilize this compound to explore structure-activity relationships in drug design, particularly for HIV and related viral infections. Its azido functionality allows for further chemical modifications, enabling the creation of novel therapeutic candidates.

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