Atomfair

Awaiting product image

Atomfair 1-Ethynyl-3-fluorobenzene 3-Fluorophenylacetylene C8H5F

Description 1-Ethynyl-3-fluorobenzene (CAS No. 2561-17-3) is a high-purity fluorinated aromatic acetylene compound with the molecular formula C8H5F . This specialized chemical building block features a terminal alkyne group adjacent to a fluorine-substituted benzene ring, offering unique reactivity for cross-coupling reactions , click chemistry , and polymer synthesis . Our product is rigorously tested by HPLC and GC to ensure ??98% purity, making it ideal for pharmaceutical intermediates, material science research, and organic synthesis applications. Supplied in amber glass vials under inert atmosphere to prevent degradation. Suitable for use in Sonogashira coupling, Huisgen cycloaddition, and as a precursor for fluorinated polyacetylenes.

Category:
Brands:

Description

Description

1-Ethynyl-3-fluorobenzene (CAS No. 2561-17-3) is a high-purity fluorinated aromatic acetylene compound with the molecular formula C8H5F. This specialized chemical building block features a terminal alkyne group adjacent to a fluorine-substituted benzene ring, offering unique reactivity for cross-coupling reactions, click chemistry, and polymer synthesis. Our product is rigorously tested by HPLC and GC to ensure ??98% purity, making it ideal for pharmaceutical intermediates, material science research, and organic synthesis applications. Supplied in amber glass vials under inert atmosphere to prevent degradation. Suitable for use in Sonogashira coupling, Huisgen cycloaddition, and as a precursor for fluorinated polyacetylenes.

  • CAS No: 2561-17-3
  • Molecular Formula: C8H5F
  • Molecular Weight: 120.12
  • Exact Mass: 120.037528322
  • Monoisotopic Mass: 120.037528322
  • IUPAC Name: 1-ethynyl-3-fluorobenzene
  • SMILES: C#CC1=CC(=CC=C1)F
  • Synonyms: 1-Ethynyl-3-fluorobenzene, 628-768-8, 3-Fluorophenylacetylene, 2561-17-3, 1-ethynyl-3-fluoro-benzene

Application

1-Ethynyl-3-fluorobenzene serves as a versatile intermediate in medicinal chemistry for introducing fluorinated phenylacetylene moieties into drug candidates. The compound is particularly valuable in PET radiopharmaceutical development where the fluorine-18 analog can be synthesized for imaging applications. Researchers utilize this building block in materials science to create fluorinated conductive polymers with enhanced thermal stability. The terminal alkyne group enables efficient participation in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation.

If you are interested or have any questions, please contact us at support@atomfair.com