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Atomfair 1-(Bromomethyl)-2,3-difluoro-benzene 2,3-Difluorobenzyl bromide C7H5BrF2

Description 1-(Bromomethyl)-2,3-difluorobenzene (CAS No. 113211-94-2) is a high-purity aromatic bromide compound with the molecular formula C7H5BrF2. This organofluorine building block features a reactive bromomethyl group adjacent to two fluorine substituents on the benzene ring, making it a versatile intermediate for synthetic chemistry applications. The compound is supplied as a clear to pale yellow liquid with typical purity ??95% (GC). It is moisture-sensitive and should be stored under inert atmosphere at 2-8??C. Ideal for nucleophilic substitution reactions, cross-coupling chemistry, and as a precursor for pharmaceutical intermediates. Available in research quantities (100mg to 100g) with optional custom packaging.

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Description

Description

1-(Bromomethyl)-2,3-difluorobenzene (CAS No. 113211-94-2) is a high-purity aromatic bromide compound with the molecular formula C7H5BrF2. This organofluorine building block features a reactive bromomethyl group adjacent to two fluorine substituents on the benzene ring, making it a versatile intermediate for synthetic chemistry applications. The compound is supplied as a clear to pale yellow liquid with typical purity ??95% (GC). It is moisture-sensitive and should be stored under inert atmosphere at 2-8??C. Ideal for nucleophilic substitution reactions, cross-coupling chemistry, and as a precursor for pharmaceutical intermediates. Available in research quantities (100mg to 100g) with optional custom packaging.

  • CAS No: 113211-94-2
  • Molecular Formula: C7H5BrF2
  • Molecular Weight: 207.01
  • Exact Mass: 205.95427
  • Monoisotopic Mass: 205.95427
  • IUPAC Name: 1-(bromomethyl)-2,3-difluorobenzene
  • SMILES: C1=CC(=C(C(=C1)F)F)CBr
  • Synonyms: benzene, 1-(bromomethyl)-2,3-difluoro-, 1-(Bromomethyl)-2,3-difluoro-benzene, 628-547-6, 2,3-Difluorobenzyl bromide, 113211-94-2

Application

This benzyl bromide derivative is widely used as a key synthetic intermediate in pharmaceutical research, particularly for the preparation of fluorinated drug candidates. The compound serves as an excellent electrophile for nucleophilic aromatic substitution reactions in medicinal chemistry. Its difluorinated aromatic structure makes it valuable for developing PET radiotracers and bioactive molecules targeting CNS disorders. The reactive bromomethyl group enables facile functionalization for structure-activity relationship studies.

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