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Atomfair 1-Bromo-4-fluorobenzene p-Bromofluorobenzene, 4-Bromofluorobenzene C6H4BrF

Description 1-Bromo-4-fluorobenzene (CAS No. 1072-85-1) is a high-purity halogenated aromatic compound with the molecular formula C6H4BrF . This colorless to pale yellow liquid is a versatile building block in organic synthesis, particularly in pharmaceutical, agrochemical, and materials science research. With a boiling point of 152-153??C and density of 1.593 g/mL at 25??C, it offers excellent reactivity for nucleophilic aromatic substitution (SNAr) reactions and metal-catalyzed cross-coupling processes. Our product is rigorously tested to ensure ??98% purity (GC), with moisture content

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Description

Description

1-Bromo-4-fluorobenzene (CAS No. 1072-85-1) is a high-purity halogenated aromatic compound with the molecular formula C6H4BrF. This colorless to pale yellow liquid is a versatile building block in organic synthesis, particularly in pharmaceutical, agrochemical, and materials science research. With a boiling point of 152-153??C and density of 1.593 g/mL at 25??C, it offers excellent reactivity for nucleophilic aromatic substitution (SNAr) reactions and metal-catalyzed cross-coupling processes. Our product is rigorously tested to ensure ??98% purity (GC), with moisture content <0.1%, making it ideal for sensitive applications. Packaged under nitrogen in amber glass bottles to prevent degradation, this compound is a critical intermediate for synthesizing liquid crystals, active pharmaceutical ingredients (APIs), and specialty polymers.

  • CAS No: 1072-85-1
  • Molecular Formula: C6H4BrF
  • Molecular Weight: 175.00
  • Exact Mass: 173.94804
  • Monoisotopic Mass: 173.94804
  • IUPAC Name: 1-bromo-4-fluorobenzene
  • SMILES: C1=CC(=CC=C1F)Br
  • Synonyms: 1-Bromo-4-fluorobenzene, 4-Bromofluorobenzene, 4-Fluorobromobenzene, p-Bromofluorobenzene, Benzene, 1-bromo-4-fluoro-

Application

1-Bromo-4-fluorobenzene serves as a key precursor in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures. It’s widely used in pharmaceutical research for developing fluorinated drug candidates, leveraging the enhanced metabolic stability imparted by the fluorine moiety. The compound also finds application in material science as a monomer for synthesizing conjugated polymers in organic electronics.

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