Description

Description

1-Amino-2-hydroxyindane (CAS No. 126456-43-7) is a high-purity organic compound with the molecular formula C₉H₁₁NO, also known by its IUPAC name 1-amino-2,3-dihydro-1H-inden-2-ol. This versatile chiral building block is widely utilized in pharmaceutical research, asymmetric synthesis, and medicinal chemistry due to its unique indane scaffold and functional groups. The compound is supplied as a white to off-white crystalline powder with ??98% purity (HPLC), ensuring exceptional quality for sensitive applications. Its molecular weight of 149.19 g/mol and well-defined structure make it ideal for studying stereoselective reactions, enzyme inhibition, and drug discovery. Proper storage at 2-8??C in a tightly sealed container under inert atmosphere is recommended to maintain stability.

Key synonyms include: 1-Amino-2-indanol, 74165-73-4, and 422-660-2. This product undergoes rigorous QC testing including NMR, HPLC, and mass spectrometry to guarantee batch-to-batch consistency for research applications. Available in quantities from milligrams to kilograms to suit various scale requirements.

Application

1-Amino-2-hydroxyindane serves as a crucial chiral synthon in asymmetric catalysis and pharmaceutical intermediate synthesis. Researchers employ this compound in developing ??-adrenergic receptor ligands and investigating neurotransmitter modulation due to its structural similarity to bioactive molecules. The hydroxyl and amino functional groups enable diverse derivatization for structure-activity relationship studies in drug discovery programs.

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