Description

Description

1-Acetylindole-2-carboxylic Acid (CAS No. 10441-26-6) is a high-purity organic compound with the molecular formula C₁₁H₉NO₃. This indole derivative features an acetyl group at the 1-position and a carboxylic acid moiety at the 2-position, making it a versatile intermediate in synthetic organic chemistry and pharmaceutical research. With a molecular weight of 203.19 g/mol, it is supplied as a fine crystalline powder, typically white to off-white in color, and is soluble in common organic solvents such as DMSO, methanol, and ethyl acetate. Ideal for researchers and scientists, this compound is rigorously tested for purity (??95% by HPLC) and is packaged under inert conditions to ensure stability. Suitable for use in heterocyclic synthesis, medicinal chemistry, and as a building block for more complex indole-based structures.

Application

1-Acetylindole-2-carboxylic Acid is widely utilized as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and bioactive indole derivatives. Its reactive carboxylic acid group enables facile derivatization, making it valuable for coupling reactions, amide formations, and heterocycle construction. Researchers employ this compound in the development of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent research. It also serves as a precursor for fluorescent probes and materials science applications.

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