Atomfair

Awaiting product image

Atomfair 1-[3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione 2′-Deoxy-2′-fluoro-5-trifluoromethyl-arabinouridine C10H10F4N2O5

Description 1-[3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione (CAS No. 114652-80-1) is a fluorinated nucleoside analog with the molecular formula C10H10F4N2O5. This high-purity compound is specifically designed for advanced research applications in medicinal chemistry, antiviral studies, and nucleoside biochemistry. Its unique structure features a trifluoromethyl-substituted pyrimidine dione coupled with a fluorinated oxolane ring, making it a valuable intermediate for probing enzyme mechanisms or developing novel therapeutics. Each batch is rigorously analyzed by HPLC, NMR, and mass spectrometry to ensure ??95% purity, and the product is supplied as a lyophilized solid under inert packaging to guarantee stability. Researchers can rely on this compound for consistent performance in…

Category:
Brands:

Description

Description

1-[3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione (CAS No. 114652-80-1) is a fluorinated nucleoside analog with the molecular formula C10H10F4N2O5. This high-purity compound is specifically designed for advanced research applications in medicinal chemistry, antiviral studies, and nucleoside biochemistry. Its unique structure features a trifluoromethyl-substituted pyrimidine dione coupled with a fluorinated oxolane ring, making it a valuable intermediate for probing enzyme mechanisms or developing novel therapeutics. Each batch is rigorously analyzed by HPLC, NMR, and mass spectrometry to ensure ??95% purity, and the product is supplied as a lyophilized solid under inert packaging to guarantee stability. Researchers can rely on this compound for consistent performance in structure-activity relationship (SAR) studies or as a reference standard.

  • CAS No: 114652-80-1
  • Molecular Formula: C10H10F4N2O5
  • Molecular Weight: 314.19
  • Exact Mass: 314.05258407
  • Monoisotopic Mass: 314.05258407
  • IUPAC Name: 1-[3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione
  • SMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)F)C(F)(F)F
  • Synonyms: 2′-Deoxy-2′-fluoro-5-trifluoromethyl-arabinouridine

Application

This fluorinated nucleoside derivative serves as a key scaffold in antiviral drug discovery, particularly for targeting viral polymerases. Its structural similarity to natural nucleosides allows investigation of enzyme inhibition mechanisms in pathogens like hepatitis or influenza viruses. Researchers also utilize it to study metabolic incorporation into nucleic acids or as a probe for fluorescence-based assays.

If you are interested or have any questions, please contact us at support@atomfair.com