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Atomfair 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine C12H18BNO3

Description 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS No. 445264-61-9) is a high-purity boronic ester derivative with the molecular formula C12H18BNO3. This compound features a pyridine core functionalized with a methoxy group at the 2-position and a pinacol boronate ester at the 5-position, making it a versatile intermediate for Suzuki-Miyaura cross-coupling reactions. Its stable dioxaborolane ring ensures excellent shelf-life and handling properties under inert conditions. Ideal for pharmaceutical research, agrochemical development, and materials science, this reagent is supplied as a crystalline solid with ??95% purity (HPLC). Store under nitrogen at 2-8??C to maintain stability.

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Description

Description

2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS No. 445264-61-9) is a high-purity boronic ester derivative with the molecular formula C12H18BNO3. This compound features a pyridine core functionalized with a methoxy group at the 2-position and a pinacol boronate ester at the 5-position, making it a versatile intermediate for Suzuki-Miyaura cross-coupling reactions. Its stable dioxaborolane ring ensures excellent shelf-life and handling properties under inert conditions. Ideal for pharmaceutical research, agrochemical development, and materials science, this reagent is supplied as a crystalline solid with ??95% purity (HPLC). Store under nitrogen at 2-8??C to maintain stability.

  • CAS No: 445264-61-9
  • Molecular Formula: C12H18BNO3
  • Molecular Weight: 235.09
  • Exact Mass: 235.1379736
  • Monoisotopic Mass: 235.1379736
  • IUPAC Name: 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CN=C(C=C2)OC
  • Synonyms: 445264-61-9, 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, DTXSID40584511, DTXCID50535276, 625-864-1

Application

This boronic ester is widely used as a key building block in palladium-catalyzed cross-coupling reactions to construct biaryl systems in drug discovery. It serves as a precursor for functionalized pyridine derivatives in medicinal chemistry and materials science. The compound’s stability and reactivity make it particularly valuable for synthesizing complex molecules in controlled environments.

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