Atomfair

Awaiting product image

Atomfair 2-Bromo-4-fluoro-1-nitrobenzene C6H3BrFNO2

Description 2-Bromo-4-fluoro-1-nitrobenzene (CAS No. 700-36-7) is a high-purity halogenated nitrobenzene derivative with the molecular formula C6H3BrFNO2. This compound is a valuable building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its structure features a bromine atom at the 2-position, a fluorine atom at the 4-position, and a nitro group at the 1-position of the benzene ring, making it a versatile intermediate for nucleophilic aromatic substitution (SNAr) reactions and cross-coupling methodologies. Supplied as a crystalline solid with >98% purity (HPLC), it is rigorously tested for consistency and stability under recommended storage conditions (2-8??C, inert atmosphere). Ideal for use in…

Category:
Brands:

Description

Description

2-Bromo-4-fluoro-1-nitrobenzene (CAS No. 700-36-7) is a high-purity halogenated nitrobenzene derivative with the molecular formula C6H3BrFNO2. This compound is a valuable building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its structure features a bromine atom at the 2-position, a fluorine atom at the 4-position, and a nitro group at the 1-position of the benzene ring, making it a versatile intermediate for nucleophilic aromatic substitution (SNAr) reactions and cross-coupling methodologies. Supplied as a crystalline solid with >98% purity (HPLC), it is rigorously tested for consistency and stability under recommended storage conditions (2-8??C, inert atmosphere). Ideal for use in Suzuki-Miyaura, Buchwald-Hartwig, and other palladium-catalyzed transformations.

  • CAS No: 700-36-7
  • Molecular Formula: C6H3BrFNO2
  • Molecular Weight: 220.00
  • Exact Mass: 218.93312
  • Monoisotopic Mass: 218.93312
  • IUPAC Name: 2-bromo-4-fluoro-1-nitrobenzene
  • SMILES: C1=CC(=C(C=C1F)Br)[N+](=O)[O-]
  • Synonyms: 2-Bromo-4-fluoro-1-nitrobenzene, 700-36-7, DTXSID60373681, DTXCID00324713, 670-950-4

Application

2-Bromo-4-fluoro-1-nitrobenzene serves as a key precursor in the synthesis of fluorinated aromatic compounds for drug discovery, particularly in the development of kinase inhibitors and antimicrobial agents. Its reactive halogen and nitro groups enable efficient derivatization to create complex heterocycles via cyclization reactions. This compound is also employed in material science for the preparation of liquid crystals and OLED intermediates.

If you are interested or have any questions, please contact us at support@atomfair.com