Description

Description

Methyl 2-fluoro-3-hydroxypropanoate (CAS No. 671-30-7) is a high-purity fluorinated ester compound with the molecular formula C₄H₇FO₃. This specialized chemical is widely utilized in organic synthesis, pharmaceutical research, and material science due to its unique fluorine-containing structure. The compound is supplied as a clear, colorless to pale yellow liquid with a characteristic ester odor, and is rigorously tested for purity (typically ??95% by GC analysis). Proper storage conditions (2-8??C under inert atmosphere) are recommended to maintain stability. Researchers value this reagent for its versatility as a building block in fluorinated compound synthesis and its potential applications in drug discovery programs targeting bioactive molecules.

Application

Methyl 2-fluoro-3-hydroxypropanoate serves as a key intermediate in the synthesis of fluorinated pharmaceutical compounds, particularly those targeting central nervous system disorders. The compound’s reactive hydroxyl and ester groups make it valuable for creating chiral building blocks in asymmetric synthesis. Researchers utilize this chemical in developing novel fluorinated analogs of biologically active molecules, where the fluorine atom can significantly alter metabolic stability and binding affinity. Its applications extend to materials science for creating specialized fluoropolymers with unique surface properties.

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