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Atomfair 2-Bromo-4-trifluoromethylaniline BTFMA C7H5BrF3N

Description 2-Bromo-4-trifluoromethylaniline (CAS No. 54403-97-3) is a high-purity halogenated aniline derivative with the molecular formula C7H5BrF3N . This compound, also known by its IUPAC name 2-bromo-4-(trifluoromethyl)aniline , is a versatile building block in organic synthesis and pharmaceutical research. Its unique structure, featuring both bromine and trifluoromethyl functional groups on an aniline backbone, makes it a valuable intermediate for the development of agrochemicals, pharmaceuticals, and specialty materials. Our product is rigorously tested to ensure ??98% purity (HPLC) and is supplied as a crystalline solid with excellent stability under recommended storage conditions (2-8??C, protected from light and moisture). Each batch is accompanied…

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Description

Description

2-Bromo-4-trifluoromethylaniline (CAS No. 54403-97-3) is a high-purity halogenated aniline derivative with the molecular formula C7H5BrF3N. This compound, also known by its IUPAC name 2-bromo-4-(trifluoromethyl)aniline, is a versatile building block in organic synthesis and pharmaceutical research. Its unique structure, featuring both bromine and trifluoromethyl functional groups on an aniline backbone, makes it a valuable intermediate for the development of agrochemicals, pharmaceuticals, and specialty materials.

Our product is rigorously tested to ensure ??98% purity (HPLC) and is supplied as a crystalline solid with excellent stability under recommended storage conditions (2-8??C, protected from light and moisture). Each batch is accompanied by comprehensive analytical data including 1H NMR, 13C NMR, and mass spectrometry reports to guarantee quality and consistency for your research needs.

Key applications include use as a precursor in: Suzuki-Miyaura cross-coupling reactions, Buchwald-Hartwig aminations, and as a scaffold for fluorinated compound libraries. The electron-withdrawing properties of the trifluoromethyl group and the reactivity of the bromine substituent make this compound particularly valuable in medicinal chemistry for structure-activity relationship studies.

  • CAS No: 54403-97-3
  • Molecular Formula: C7H5BrF3N
  • Molecular Weight: 240.02
  • Exact Mass: 238.95575
  • Monoisotopic Mass: 238.95575
  • IUPAC Name: 2-bromo-4-(trifluoromethyl)aniline
  • SMILES: C1=CC(=C(C=C1C(F)(F)F)Br)N
  • Synonyms: 57946-63-1, 2-Bromo-4-trifluoromethylaniline, EINECS 261-035-7, DTXSID60206667, BTFMA

Application

2-Bromo-4-trifluoromethylaniline serves as a key intermediate in pharmaceutical research, particularly in the synthesis of trifluoromethyl-containing drug candidates where enhanced metabolic stability and lipophilicity are desired. The compound is widely utilized in palladium-catalyzed cross-coupling reactions to create biaryl structures common in many active pharmaceutical ingredients. Its unique electronic properties make it valuable for developing agrochemicals with improved activity profiles, especially in the creation of novel pesticides and herbicides.

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