Description

Description

Diethyl (2-bromoethyl)phosphonate (CAS No. 5324-30-1) is a highly versatile organophosphorus compound with the molecular formula C₆H₁₄BrO₃P. This brominated phosphonate ester is widely utilized in organic synthesis, particularly in the preparation of phosphonate derivatives and as a key intermediate in the Horner-Wadsworth-Emmons (HWE) reaction. Its IUPAC name, 1-bromo-2-diethoxyphosphorylethane, reflects its structural features, which include a reactive bromoethyl group and a diethoxyphosphoryl moiety. This compound is available in high purity (>95%) and is packaged under inert conditions to ensure stability and longevity. Ideal for researchers and chemists working in pharmaceuticals, agrochemicals, and material science, Diethyl (2-bromoethyl)phosphonate offers excellent reactivity for C-C bond formation and functional group transformations.

Application

Diethyl (2-bromoethyl)phosphonate is primarily used as a reagent in the Horner-Wadsworth-Emmons reaction for the synthesis of ??,??-unsaturated esters and related compounds. It serves as a key intermediate in the preparation of phosphonate-based ligands and organocatalysts. Additionally, this compound finds applications in the synthesis of bioactive molecules and agrochemicals due to its ability to introduce phosphonate groups into organic frameworks.

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