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Atomfair Ethyl 4-bromo-2-fluorobenzoate C9H8BrFO2

Description Ethyl 4-bromo-2-fluorobenzoate (CAS No. 474709-71-2) is a high-purity aromatic ester compound with the molecular formula C9H8BrFO2. This organobromine derivative features a benzoate core substituted with a bromine atom at the para position and a fluorine atom at the ortho position, esterified with an ethyl group. With a molecular weight of 247.06 g/mol, this crystalline solid is widely utilized as a key intermediate in pharmaceutical synthesis and advanced material research. Our product is rigorously tested by HPLC and NMR to ensure >98% purity, packaged under inert gas to prevent degradation. Ideal for coupling reactions, halogen exchange processes, and as a…

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Description

Description

Ethyl 4-bromo-2-fluorobenzoate (CAS No. 474709-71-2) is a high-purity aromatic ester compound with the molecular formula C9H8BrFO2. This organobromine derivative features a benzoate core substituted with a bromine atom at the para position and a fluorine atom at the ortho position, esterified with an ethyl group. With a molecular weight of 247.06 g/mol, this crystalline solid is widely utilized as a key intermediate in pharmaceutical synthesis and advanced material research. Our product is rigorously tested by HPLC and NMR to ensure >98% purity, packaged under inert gas to prevent degradation. Ideal for coupling reactions, halogen exchange processes, and as a precursor for fluorinated liquid crystals or bioactive molecules.

  • CAS No: 474709-71-2
  • Molecular Formula: C9H8BrFO2
  • Molecular Weight: 247.06
  • Exact Mass: 245.96917
  • Monoisotopic Mass: 245.96917
  • IUPAC Name: ethyl 4-bromo-2-fluorobenzoate
  • SMILES: CCOC(=O)C1=C(C=C(C=C1)Br)F
  • Synonyms: Ethyl 4-bromo-2-fluorobenzoate, Benzoic acid, 4-bromo-2-fluoro-, ethyl ester, DTXSID20621812, DTXCID10572566, 812-997-7

Application

Ethyl 4-bromo-2-fluorobenzoate serves as a versatile building block in medicinal chemistry for the synthesis of fluorinated drug candidates, particularly kinase inhibitors and CNS-active compounds. The compound’s orthogonal halogen/fluorine substitution pattern enables selective Suzuki-Miyaura cross-coupling reactions in API development. Researchers also employ it as a precursor for nonlinear optical materials and as a derivatization agent in analytical chemistry for halogenated aromatic detection.

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