Description

Description

3-Nitropyridin-2-ylamine (CAS No. 4545-18-0) is a high-purity nitropyridine derivative with the molecular formula C₅H₅N₃O₂. This compound, also known as 2-Amino-3-nitropyridine, is a valuable heterocyclic building block for pharmaceutical, agrochemical, and materials science research. Its IUPAC name is 3-nitropyridin-2-amine, and it features a nitro group at the 3-position and an amino group at the 2-position of the pyridine ring, offering versatile reactivity for nucleophilic and electrophilic substitutions.

Our product is synthesized under strict quality control measures, ensuring ??98% purity (HPLC) with trace impurities rigorously characterized. It is supplied as a fine yellow to orange crystalline powder, soluble in organic solvents like DMSO, methanol, and acetonitrile, but with limited solubility in water. Each batch undergoes thorough analytical validation (NMR, LC-MS, FTIR) to guarantee consistency for synthetic applications.

Packaging options range from 1g research samples to 1kg bulk quantities, with all containers sealed under inert gas to prevent degradation. SDS and technical data sheets are provided with every order. Store in a cool, dry place (2-8??C recommended) protected from light.

Application

3-Nitropyridin-2-ylamine serves as a key intermediate in the synthesis of pharmaceutical compounds, particularly for developing kinase inhibitors and antimicrobial agents. Researchers utilize this compound in palladium-catalyzed cross-coupling reactions to construct complex heterocyclic systems. In material science, it functions as a precursor for photoactive dyes and coordination complexes with transition metals. The nitro and amino groups provide orthogonal reactivity for sequential functionalization in multi-step syntheses.

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