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Atomfair 4-Bromo-2-(trifluoromethyl)aniline C7H5BrF3N

Description 4-Bromo-2-(trifluoromethyl)aniline (CAS No. 454-79-5) is a high-purity aromatic amine compound with the molecular formula C7H5BrF3N . This halogenated aniline derivative features a bromo substituent at the para position and a trifluoromethyl group at the ortho position relative to the amino group, offering unique electronic and steric properties for advanced synthetic applications. The compound is supplied as a crystalline solid with ??98% purity (HPLC) and is rigorously tested for consistency in moisture content, heavy metals, and residual solvents. Suitable for use as a key intermediate in pharmaceutical development, agrochemical synthesis, and materials science research. Store under inert atmosphere at 2-8??C…

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Description

Description

4-Bromo-2-(trifluoromethyl)aniline (CAS No. 454-79-5) is a high-purity aromatic amine compound with the molecular formula C7H5BrF3N. This halogenated aniline derivative features a bromo substituent at the para position and a trifluoromethyl group at the ortho position relative to the amino group, offering unique electronic and steric properties for advanced synthetic applications. The compound is supplied as a crystalline solid with ??98% purity (HPLC) and is rigorously tested for consistency in moisture content, heavy metals, and residual solvents. Suitable for use as a key intermediate in pharmaceutical development, agrochemical synthesis, and materials science research. Store under inert atmosphere at 2-8??C to maintain stability.

Key Attributes:

  • IUPAC Name: 4-bromo-2-(trifluoromethyl)aniline
  • Molecular Weight: 240.02 g/mol
  • Melting Point: 45-48??C
  • Density: 1.72 g/cm3
  • Packaging Options: 1g, 5g, 25g sealed amber glass vials
  • CAS No: 454-79-5
  • Molecular Formula: C7H5BrF3N
  • Molecular Weight: 240.02
  • Exact Mass: 238.95575
  • Monoisotopic Mass: 238.95575
  • IUPAC Name: 4-bromo-2-(trifluoromethyl)aniline
  • SMILES: C1=CC(=C(C=C1Br)C(F)(F)F)N
  • Synonyms: 4-Bromo-2-(trifluoromethyl)aniline, Benzenamine, 4-bromo-2-(trifluoromethyl)-, 4-Bromo-alpha,alpha,alpha-trifluoro-o-toluidine, LY2Y65FS45, EINECS 207-150-8

Application

4-Bromo-2-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry for the synthesis of trifluoromethylated bioactive compounds. The electron-withdrawing trifluoromethyl group enhances metabolic stability in drug candidates, while the bromo substituent enables further functionalization via cross-coupling reactions. This intermediate is particularly valuable in developing kinase inhibitors and antimicrobial agents. In material science, it contributes to the synthesis of liquid crystals and OLED materials due to its polarized aromatic structure.

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