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Atomfair 2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine C11H15BFNO2

Description 2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS No. 452972-14-4) is a high-purity boronic ester derivative with the molecular formula C11H15BFNO2. This compound features a pyridine ring substituted with a fluorine atom at the 2-position and a pinacol boronate ester at the 3-position, making it a versatile intermediate for Suzuki-Miyaura cross-coupling reactions and other transition-metal-catalyzed transformations. Its stability under ambient conditions and compatibility with diverse reaction conditions make it ideal for pharmaceutical, agrochemical, and materials science research. Available in >95% purity (HPLC), this reagent is supplied in rigorously dried packaging to ensure optimal shelf life and performance. Store under inert atmosphere at 2-8??C for long-term…

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Description

Description

2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS No. 452972-14-4) is a high-purity boronic ester derivative with the molecular formula C11H15BFNO2. This compound features a pyridine ring substituted with a fluorine atom at the 2-position and a pinacol boronate ester at the 3-position, making it a versatile intermediate for Suzuki-Miyaura cross-coupling reactions and other transition-metal-catalyzed transformations. Its stability under ambient conditions and compatibility with diverse reaction conditions make it ideal for pharmaceutical, agrochemical, and materials science research. Available in >95% purity (HPLC), this reagent is supplied in rigorously dried packaging to ensure optimal shelf life and performance. Store under inert atmosphere at 2-8??C for long-term stability.

  • CAS No: 452972-14-4
  • Molecular Formula: C11H15BFNO2
  • Molecular Weight: 223.05
  • Exact Mass: 223.1179870
  • Monoisotopic Mass: 223.1179870
  • IUPAC Name: 2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2=C(N=CC=C2)F
  • Synonyms: 452972-14-4, 2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, DTXSID40476866, DTXCID40427676, 670-324-0

Application

This compound is widely used as a key building block in medicinal chemistry for the synthesis of fluorinated pyridine derivatives, which are prevalent in drug discovery. It serves as a crucial intermediate in Suzuki-Miyaura cross-coupling reactions to form biaryl structures. Researchers also employ it in the development of boron-containing probes for biochemical assays and PET tracer synthesis.

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