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Atomfair Jolkinolide B C20H26O4

Description Jolkinolide B (CAS 452-84-6) is a bioactive diterpenoid lactone with the molecular formula C20H26O4. It is a natural product derived from Euphorbia species and exhibits a complex hexacyclic structure, as defined by its IUPAC name: (1S,3R,8R,10R,11R,12R,17R)-5,12,16,16-tetramethyl-2,7,9-trioxahexacyclo[9.8.0.01,3.04,8.08,10.012,17]nonadec-4-en-6-one. This compound is of high purity (>95% by HPLC) and is supplied as a white to off-white crystalline powder, ideal for research applications in pharmacology, natural product chemistry, and drug discovery. Jolkinolide B is known for its potential anti-inflammatory, anti-tumor, and immunomodulatory properties, making it a valuable reference standard for biochemical studies. Store at -20??C in a tightly sealed container to maintain stability.

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Description

Description

Jolkinolide B (CAS 452-84-6) is a bioactive diterpenoid lactone with the molecular formula C20H26O4. It is a natural product derived from Euphorbia species and exhibits a complex hexacyclic structure, as defined by its IUPAC name: (1S,3R,8R,10R,11R,12R,17R)-5,12,16,16-tetramethyl-2,7,9-trioxahexacyclo[9.8.0.01,3.04,8.08,10.012,17]nonadec-4-en-6-one. This compound is of high purity (>95% by HPLC) and is supplied as a white to off-white crystalline powder, ideal for research applications in pharmacology, natural product chemistry, and drug discovery. Jolkinolide B is known for its potential anti-inflammatory, anti-tumor, and immunomodulatory properties, making it a valuable reference standard for biochemical studies. Store at -20??C in a tightly sealed container to maintain stability.

  • CAS No: 452-84-6
  • Molecular Formula: C20H26O4
  • Molecular Weight: 330.4
  • Exact Mass: 330.18310931
  • Monoisotopic Mass: 330.18310931
  • IUPAC Name: (1S,3R,8R,10R,11R,12R,17R)-5,12,16,16-tetramethyl-2,7,9-trioxahexacyclo[9.8.0.01,3.04,8.08,10.012,17]nonadec-4-en-6-one
  • SMILES: CC1=C2[C@@H]3[C@]4(O3)CC[C@H]5[C@]([C@@H]4[C@@H]6[C@]2(O6)OC1=O)(CCCC5(C)C)C
  • Synonyms: Jolkinolide B, 37905-08-1, (1S,3R,8R,10R,11R,12R,17R)-5,12,16,16-tetramethyl-2,7,9-trioxahexacyclo[9.8.0.01,3.04,8.08,10.012,17]nonadec-4-en-6-one, Bisoxireno(1,10a:3,4)phenanthro(3,2-b)furan-9(7aH)-one, 1,2,3,4,4a,5,6,11a,11b,11c-decahydro-4,4,8,11c-tetramethyl-, (4aR-(4aalpha,6aS*,7abeta,10aR*,11abeta,11balpha,11cbeta))-, (1S,3R,8R,10R,11R,12R,17R)-5,12,16,16-tetramethyl-2,7,9-trioxahexacyclo(9.8.0.01,3.04,8.08,10.012,17)nonadec-4-en-6-one

Application

Jolkinolide B is widely studied for its pharmacological activities, including anti-cancer effects through modulation of apoptosis and cell cycle pathways. Researchers utilize it as a reference compound in natural product isolation and structural elucidation studies. Its immunomodulatory properties make it relevant for investigating inflammatory and autoimmune disease mechanisms.

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