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Atomfair 4-Bromo-2-(trifluoromethyl)aniline C7H5BrF3N

Description 4-Bromo-2-(trifluoromethyl)aniline (CAS No. 445-02-3) is a high-purity halogenated aniline derivative with the molecular formula C7H5BrF3N. This compound features a bromo substituent at the para position and a trifluoromethyl group at the ortho position relative to the aniline nitrogen, offering unique electronic and steric properties for advanced synthetic applications. With a molecular weight of 240.02 g/mol, it is a versatile building block in pharmaceutical, agrochemical, and materials science research. Available in >98% purity (HPLC), it is supplied in sealed containers under inert gas to ensure stability. Ideal for Suzuki couplings, nucleophilic substitutions, and as a precursor for heterocyclic synthesis. Store…

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Description

Description

4-Bromo-2-(trifluoromethyl)aniline (CAS No. 445-02-3) is a high-purity halogenated aniline derivative with the molecular formula C7H5BrF3N. This compound features a bromo substituent at the para position and a trifluoromethyl group at the ortho position relative to the aniline nitrogen, offering unique electronic and steric properties for advanced synthetic applications. With a molecular weight of 240.02 g/mol, it is a versatile building block in pharmaceutical, agrochemical, and materials science research. Available in >98% purity (HPLC), it is supplied in sealed containers under inert gas to ensure stability. Ideal for Suzuki couplings, nucleophilic substitutions, and as a precursor for heterocyclic synthesis. Store in a cool, dry place away from light and moisture.

  • CAS No: 445-02-3
  • Molecular Formula: C7H5BrF3N
  • Molecular Weight: 240.02
  • Exact Mass: 238.95575
  • Monoisotopic Mass: 238.95575
  • IUPAC Name: 4-bromo-2-(trifluoromethyl)aniline
  • SMILES: C1=CC(=C(C=C1Br)C(F)(F)F)N
  • Synonyms: 4-Bromo-2-(trifluoromethyl)aniline, Benzenamine, 4-bromo-2-(trifluoromethyl)-, 4-Bromo-alpha,alpha,alpha-trifluoro-o-toluidine, LY2Y65FS45, EINECS 207-150-8

Application

4-Bromo-2-(trifluoromethyl)aniline is widely used as a key intermediate in the synthesis of bioactive molecules, including pharmaceuticals and agrochemicals. Its electron-withdrawing trifluoromethyl group enhances reactivity in cross-coupling reactions, such as Buchwald-Hartwig aminations. Researchers also employ it to develop liquid crystals and OLED materials due to its polarizable aromatic core. The bromo substituent allows further functionalization via palladium-catalyzed transformations.

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