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Atomfair 2-Bromo-4,6-Difluoroaniline C6H4BrF2N

Description 2-Bromo-4,6-Difluoroaniline (CAS No. 444-14-4) is a high-purity halogenated aniline derivative with the molecular formula C6H4BrF2N . This compound is a valuable building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring bromine and fluorine substituents on the aromatic ring, enhances reactivity and selectivity in cross-coupling reactions. Available in >98% purity (GC), it is supplied as a crystalline solid with strict quality control to ensure consistency for sensitive applications. Ideal for Suzuki-Miyaura couplings, Buchwald-Hartwig aminations, and other palladium-catalyzed transformations. Store under inert conditions at 2-8??C to maintain stability.

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Description

Description

2-Bromo-4,6-Difluoroaniline (CAS No. 444-14-4) is a high-purity halogenated aniline derivative with the molecular formula C6H4BrF2N. This compound is a valuable building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring bromine and fluorine substituents on the aromatic ring, enhances reactivity and selectivity in cross-coupling reactions. Available in >98% purity (GC), it is supplied as a crystalline solid with strict quality control to ensure consistency for sensitive applications. Ideal for Suzuki-Miyaura couplings, Buchwald-Hartwig aminations, and other palladium-catalyzed transformations. Store under inert conditions at 2-8??C to maintain stability.

  • CAS No: 444-14-4
  • Molecular Formula: C6H4BrF2N
  • Molecular Weight: 208.00
  • Exact Mass: 206.94952
  • Monoisotopic Mass: 206.94952
  • IUPAC Name: 2-bromo-4,6-difluoroaniline
  • SMILES: C1=C(C=C(C(=C1F)N)Br)F
  • Synonyms: 2-Bromo-4,6-Difluoroaniline, WUJKFVGKLTWVSQ-UHFFFAOYSA-, DTXSID00196154, EC 429-430-0, NSC 93389

Application

2-Bromo-4,6-Difluoroaniline serves as a key intermediate in the synthesis of bioactive molecules, including kinase inhibitors and antimicrobial agents. Its electron-deficient aromatic ring facilitates nucleophilic aromatic substitution (SNAr) reactions in drug discovery. The compound is also used in materials science for developing liquid crystals and OLED precursors. Researchers leverage its halogenated structure for ortho-directed metalation in complex molecule assembly.

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