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Atomfair Distamycin A/5 C34H39N13O6

Description Distamycin A/5 (CAS 407-20-5) is a highly specialized oligopeptide antibiotic and minor groove DNA binder, featuring the molecular formula C34H39N13O6. This compound is a derivative of Distamycin A, characterized by its unique pyrrole-2-carboxamide structure and amidinoethyl side chain. As a research-grade biochemical, it is provided as a hydrochloride salt with ??95% purity (HPLC), ensuring consistency for experimental use. The product is supplied as a lyophilized powder, packaged under inert gas to maintain stability, and should be stored at -20??C. Distamycin A/5 is particularly valuable for studying DNA-protein interactions, antimicrobial mechanisms, and as a scaffold for designing sequence-specific DNA-binding agents.…

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Description

Description

Distamycin A/5 (CAS 407-20-5) is a highly specialized oligopeptide antibiotic and minor groove DNA binder, featuring the molecular formula C34H39N13O6. This compound is a derivative of Distamycin A, characterized by its unique pyrrole-2-carboxamide structure and amidinoethyl side chain. As a research-grade biochemical, it is provided as a hydrochloride salt with ??95% purity (HPLC), ensuring consistency for experimental use. The product is supplied as a lyophilized powder, packaged under inert gas to maintain stability, and should be stored at -20??C. Distamycin A/5 is particularly valuable for studying DNA-protein interactions, antimicrobial mechanisms, and as a scaffold for designing sequence-specific DNA-binding agents. Its high affinity for AT-rich DNA sequences makes it a useful tool for molecular biology and medicinal chemistry research.

  • CAS No: 407-20-5
  • Molecular Formula: C34H39N13O6
  • Molecular Weight: 725.8
  • Exact Mass: 725.31462601
  • Monoisotopic Mass: 725.31462601
  • IUPAC Name: N-[5-[[5-[[5-[[5-[(3-amino-3-iminopropyl)carbamoyl]-1-methylpyrrol-3-yl]carbamoyl]-1-methylpyrrol-3-yl]carbamoyl]-1-methylpyrrol-3-yl]carbamoyl]-1-methylpyrrol-3-yl]-4-formamido-1-methylpyrrole-2-carboxamide
  • SMILES: CN1C=C(C=C1C(=O)NC2=CN(C(=C2)C(=O)NC3=CN(C(=C3)C(=O)NC4=CN(C(=C4)C(=O)NC5=CN(C(=C5)C(=O)NCCC(=N)N)C)C)C)C)NC=O
  • Synonyms: Distamycin A/5, Distamycin A5, N,4′:N’,4”:N”,4”’:N”’,4””-Penta(pyrrole-2-carboxamide), N””-(2-amidinoethyl)-4-formamido-1,1′,1”,1”’,1””-pentamethyl-, hydrochloride, CHEMBL1182832, A6798

Application

Distamycin A/5 is primarily used in biochemical research as a model compound for studying minor groove DNA binding interactions. It serves as a tool for investigating antimicrobial mechanisms due to its ability to inhibit DNA-dependent processes. Researchers utilize this molecule in structural studies of DNA-ligand complexes and as a starting point for developing novel gene-targeting therapeutics. Its sequence-specific binding properties make it valuable for chromatin analysis and nucleic acid recognition studies.

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