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Atomfair 4-Fluorobenzoyl chloride p-Fluorobenzoyl chloride C7H4ClFO

Description 4-Fluorobenzoyl chloride (CAS No. 403-43-0) is a highly reactive organic compound with the molecular formula C7H4ClFO . This aromatic acyl chloride is a clear to pale yellow liquid with a pungent odor, commonly used as a key intermediate in organic synthesis and pharmaceutical manufacturing. Its structure features a fluorine substituent at the para position of the benzoyl chloride group, enhancing its reactivity in nucleophilic substitution and acylation reactions. Suitable for laboratory and industrial applications, this compound is stored under inert conditions to prevent hydrolysis. Available in high purity grades (??98%), it is ideal for researchers requiring precise and reliable…

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Description

Description

4-Fluorobenzoyl chloride (CAS No. 403-43-0) is a highly reactive organic compound with the molecular formula C7H4ClFO. This aromatic acyl chloride is a clear to pale yellow liquid with a pungent odor, commonly used as a key intermediate in organic synthesis and pharmaceutical manufacturing. Its structure features a fluorine substituent at the para position of the benzoyl chloride group, enhancing its reactivity in nucleophilic substitution and acylation reactions. Suitable for laboratory and industrial applications, this compound is stored under inert conditions to prevent hydrolysis. Available in high purity grades (??98%), it is ideal for researchers requiring precise and reliable reagents for complex chemical transformations.

  • CAS No: 403-43-0
  • Molecular Formula: C7H4ClFO
  • Molecular Weight: 158.56
  • Exact Mass: 157.9934706
  • Monoisotopic Mass: 157.9934706
  • IUPAC Name: 4-fluorobenzoyl chloride
  • SMILES: C1=CC(=CC=C1C(=O)Cl)F
  • Synonyms: 4-Fluorobenzoyl chloride, 403-43-0, Benzoyl chloride, 4-fluoro-, p-Fluorobenzoyl chloride, Benzoyl chloride, p-fluoro-

Application

4-Fluorobenzoyl chloride is widely employed as a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It serves as a critical intermediate in the preparation of fluorinated benzophenones, amides, and esters through acylation reactions. Researchers utilize it in peptide coupling and polymer chemistry due to its high reactivity with nucleophiles. Its fluorine moiety enhances the metabolic stability of derived compounds, making it valuable in drug discovery.

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