Description

Description

Methyl Trifluoromethanesulfonate (MeOTf) is a highly reactive and versatile alkylating agent widely used in organic synthesis and pharmaceutical research. With the molecular formula C₂H₃F₃O₃S and CAS number 333-27-7, this colorless to pale yellow liquid is known for its strong electrophilic properties, making it an excellent reagent for introducing methyl groups into nucleophilic substrates. Its triflate group (^–OSO₂CF₃) ensures superior leaving-group ability, facilitating efficient reactions in challenging transformations. Packaged under inert conditions to ensure stability, our high-purity Methyl Trifluoromethanesulfonate is ideal for demanding applications in peptide synthesis, carbohydrate chemistry, and catalytic processes. Store in a cool, dry place away from moisture and handle with appropriate safety precautions due to its corrosive nature.

Application

Methyl Trifluoromethanesulfonate is extensively used as a potent methylating agent in organic synthesis, particularly for O-, N-, and S-methylation reactions. It serves as a key reagent in the preparation of pharmaceutical intermediates, agrochemicals, and specialty chemicals. Its high reactivity makes it valuable in Lewis acid-catalyzed reactions and as a promoter in glycosylation reactions for carbohydrate chemistry. Researchers also employ it in polymer science for modifying functional groups on polymer backbones. Due to its moisture sensitivity, reactions involving MeOTf typically require anhydrous conditions.

If you are interested or have any questions, please contact us at support@atomfair.com