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Atomfair Avanafil [‘STENDRA’, ‘Spedra’, ‘TA-1790’] C23H26ClN7O3
Description Avanafil (CAS No. 330785-81-4) is a highly selective and potent phosphodiesterase type 5 (PDE5) inhibitor with the molecular formula C23H26ClN7O3. This pharmaceutical compound, known by its IUPAC name 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide , is widely recognized for its rapid onset of action and favorable safety profile. Avanafil is specifically designed for the treatment of erectile dysfunction (ED), offering researchers a valuable tool for studying PDE5 inhibition mechanisms. Available in high-purity form, this compound is ideal for pharmacological studies, drug development, and biochemical research. Each batch is rigorously tested for quality, ensuring consistency and reliability for scientific applications.
Description
Description
Avanafil (CAS No. 330785-81-4) is a highly selective and potent phosphodiesterase type 5 (PDE5) inhibitor with the molecular formula C23H26ClN7O3. This pharmaceutical compound, known by its IUPAC name 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide, is widely recognized for its rapid onset of action and favorable safety profile. Avanafil is specifically designed for the treatment of erectile dysfunction (ED), offering researchers a valuable tool for studying PDE5 inhibition mechanisms. Available in high-purity form, this compound is ideal for pharmacological studies, drug development, and biochemical research. Each batch is rigorously tested for quality, ensuring consistency and reliability for scientific applications.
- CAS No: 330785-81-4
- Molecular Formula: C23H26ClN7O3
- Molecular Weight: 483.9
- Exact Mass: 483.1785654
- Monoisotopic Mass: 483.1785654
- IUPAC Name: 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
- SMILES: COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCC[C@H]4CO)Cl
- Synonyms: Avanafil, 330784-47-9, STENDRA, Spedra, TA-1790
Application
Avanafil is primarily used in research settings to investigate its mechanism of action as a PDE5 inhibitor, which enhances blood flow to specific tissues. Its rapid absorption and selectivity make it a valuable compound for studying erectile dysfunction treatments. Researchers also explore its potential applications in pulmonary arterial hypertension (PAH) due to its vasodilatory effects. Additionally, Avanafil serves as a reference standard in analytical chemistry for method development and validation.
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