Description

Description

4-Fluoro-3-methylbenzoic acid (CAS No. 321-12-0) is a high-purity fluorinated aromatic carboxylic acid with the molecular formula C₈H₇FO₂. This compound is a valuable intermediate in organic synthesis and pharmaceutical research, featuring a fluorine substituent at the para position and a methyl group at the meta position relative to the carboxylic acid functionality. Its well-defined structure and reactivity make it ideal for coupling reactions, derivatization, and as a building block for advanced materials. Available in >98% purity (HPLC), this product is rigorously tested for consistency, ensuring reliable performance in sensitive applications. Packaged under inert gas to prevent degradation, it is supplied as a white to off-white crystalline powder with excellent shelf stability.

Application

4-Fluoro-3-methylbenzoic acid is widely used as a key precursor in the synthesis of pharmaceuticals, agrochemicals, and liquid crystal materials. Its fluorine moiety enhances metabolic stability in drug candidates, making it valuable for medicinal chemistry. Researchers also employ it in Suzuki-Miyaura cross-coupling reactions to create biaryl structures. Additionally, it serves as a derivatization agent in analytical chemistry for detecting trace compounds.

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